PMID: 8588566Dec 1, 1995Paper

Prospective assessment of fecundability of female semiconductor workers

American Journal of Industrial Medicine
B EskenaziM B Schenker

Abstract

To investigate a possible effect of reduced fecundability (probability of conception per menstrual cycle) among women who fabricate silicon wafers, 152 fabrication-room (fab) and 251 nonfab workers were followed for an average of five menstrual cycles. Daily urine samples were analyzed to confirm clinical spontaneous abortions (SABs) and early fetal losses (EFLs). Adjusted fecundability odds ratios (FRs) for fab workers ranged from 0.59 to 0.72 (p = 0.09-0.28 vs. nonfab). For clinical pregnancies only, the adjusted FR ranged from 0.43-0.50 (p = 0.04-0.09 vs. nonfab). This lower fecundability was most pronounced among dopants and thin-film workers [adjusted FR = 0.61, 95% confidence interval (CI) = 0.27-1.40 for all pregnancies; adjusted FR = 0.22, 95% CI = 0.05-0.96 for clinical pregnancies] and in workers exposed to ethylene-based glycol ethers (adjusted FR = 0.37, 95% CI = 0.11-1.19).

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Citations

Apr 5, 2003·Environmental Health Perspectives·Pete N LohstrohBill L Lasley
May 30, 2008·International Journal of Occupational and Environmental Health·Ching-Chun LinPau-Chung Chen
Jan 8, 2009·American Journal of Epidemiology·Jane KeyNiels Keiding
Jan 17, 2012·American Journal of Epidemiology·Donna D Baird, Anne Z Steiner
Jul 8, 2014·International Journal of Occupational and Environmental Health·Myoung-Hee KimDomyung Paek
Dec 1, 1995·American Journal of Industrial Medicine·B EskenaziM B Schenker
Dec 1, 1995·American Journal of Industrial Medicine·M B SchenkerS H Swan
Jun 14, 2000·Critical Reviews in Toxicology·G Johanson
Jan 18, 2003·Archives of Environmental Health·Randa A El-ZeinMarvin S Legator
May 10, 2008·Occupational Medicine·Ching-Chun LinPau-Chung Chen
Jul 6, 2004·American Journal of Epidemiology·Yan LiuWesley O Johnson
Jul 11, 2013·Environmental Health Perspectives·Ronan GarlantézecSylvaine Cordier
Jun 11, 1999·American Journal of Industrial Medicine·M L Lindbohm
Dec 31, 2003·Environmental Health Perspectives·Germaine M BuckSteven M Schrader

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