Prospective Assessment of Outcomes After Primary Unipolar, Multisurface, and Bipolar Osteochondral Allograft Transplantations in the Knee: A Comparison of 2 Preservation Methods

The American Journal of Sports Medicine
James P Stannard, James L Cook

Abstract

Articular cartilage lesions in the knee remain a challenging clinical problem. A novel graft preservation method combined with surgical technique and patient management improvements would lead to consistently successful outcomes after osteochondral allograft (OCA) transplantation. Cohort study; Level of evidence, 3. With institutional review board approval and informed consent, patients were prospectively enrolled into a registry to follow outcomes after OCA transplantation. Patients were included when ≥1-year follow-up data were available, including complications and reoperations, patient-reported outcome measures (PROMs), compliance with rehabilitation, revisions, and failures. For patients meeting inclusion criteria (N = 194), mean ± SD age was 37.9 ± 12.2 years and mean BMI was 28.9 ± 5; 38% received unipolar transplants (44% multisurface) and 62% received bipolar transplants. OCAs were preserved by standard tissue bank methods (standard preservation [SP]; 29%) or the novel method (Missouri Osteochondral Preservation System [MOPS]; 71%). Initial success rates were 79% for all cases combined, 60% for SP, and 84% for MOPS. MOPS cases were significantly (P = .028) more likely to be associated with successful outcomes when comp...Continue Reading

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Citations

Mar 22, 2020·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·Anna J SchreinerJames L Cook
Jun 26, 2020·The Journal of Knee Surgery·Anna J SchreinerJames L Cook
Nov 25, 2020·The Journal of Knee Surgery·Alexander HoorntjeRutger C I van Geenen
Jul 21, 2020·The Journal of Knee Surgery·James P StannardAnna J Schreiner
Jan 4, 2021·The Journal of Knee Surgery·Nathan W SkelleyBenjamin Noonan
Oct 29, 2020·The Journal of Knee Surgery·Cory R CreceliusRobert Schaal
Aug 26, 2021·Arthroscopy, Sports Medicine, and Rehabilitation·Anirudh K GowdBrian R Waterman
Oct 3, 2021·The Journal of Knee Surgery·Kyle D PaulAmit M Momaya
Aug 28, 2021·Journal of the American Veterinary Medical Association

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