Prospective cohort study of three- versus two-dimensional ultrasound for prediction of oocyte maturity

Fertility and Sterility
Doron ShmorgunRobin Roberts

Abstract

To determine whether three-dimensional follicular ultrasound (3-D) measurements are better predictors of optimal timing of hCG administration than two-dimensional (2-D) images, the current standard. Prospective, cohort study. Tertiary referral center. Seventy-six patients undergoing IVF. Seventy-six consecutive patients undergoing serial follicular monitoring during IVF had an additional daily 3-D volume scan of their ovaries once lead follicles had reached 16 mm diameter. Number of mature oocytes retrieved. The 2-D follicular diameter measurements predicted 25.4% of the observed variance in the number of mature oocytes retrieved. The 3-D follicular volume measurements were more predictive of outcome, accounting for 29.2% of the observed variance in number of mature oocytes retrieved. Follicles >22 mm diameter and 5 mL volume were associated with fewer mature oocytes reflecting an undesired postmature state. Follicles measuring 11 to 15 mm had a 50% chance of yielding a mature oocyte. Three-dimensional follicular volume measurements have a stronger correlation with the number of mature oocytes retrieved than 2-D measurements. As 3-D technology improves, this parameter may replace 2-D measurements in the optimal timing of hCG be...Continue Reading

References

Feb 1, 1996·Fertility and Sterility·A Kyei-MensahS L Tan
May 30, 2003·Archives of Gynecology and Obstetrics·Ahmed AmerAbdel-Al Ghandour

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Citations

Sep 6, 2015·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·Neeta SinghPerumal Vanamail
Jan 17, 2015·Frontiers in Surgery·Frank VandekerckhovePetra De Sutter
Mar 25, 2014·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·Amelia RodriguezValerie Vernaeve
Feb 9, 2017·Annals of Clinical Biochemistry·M PeaveyS Devaraj

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