Prospective comparison of a fast 1.5-T biparametric with the 3.0-T multiparametric ESUR magnetic resonance imaging protocol as a triage test for men at risk of prostate cancer

BJU International
Sandy Van NieuwenhoveBertrand Tombal

Abstract

To compare prospectively the diagnostic performance of a biparametric (T2-weighted imaging [T2WI] and diffusion-weighted imaging [DWI]) 1.5-T fast magnetic resonance imaging (fMRI) protocol with the standard 3.0-T multiparametric MRI (mpMRI) protocol of the European Society of Urological Imaging (ESUR) in men referred for a prostate biopsy. Ninety patients with a prostate cancer (PCa) risk of ≥10% according to the SWOP calculator 4 underwent first fMRI and then the reference mpMRI. Patients with Prostate Imaging Reporting and Data System (PI-RADS) v.2 lesions ≥3/5 on the mpMRI were scheduled for MRI/ultrasonography (US) fusion-guided prostate biopsy. Performance of fMRI was assessed using receiver-operating characteristic curve analysis and mpMRI as reference. Calculation of inter-technique agreement on PI-RADS v.2 score by Cohen's κ. The diagnostic accuracy of fMRI shown by the lesion-based analysis was excellent: area under the curve (AUC) 0.961 (P < 0.001), sensitivity 95%, specificity 97%, positive predictive value (PPV) 99%, negative predictive value (NPV) 89%. The patient-based analysis showed an AUC for fMRI of 0.975 (P < 0.001), a sensitivity of 98%, a specificity of 97%, a PPV of 98% and an NPV of 97%. Agreement on the...Continue Reading

References

Dec 1, 1982·British Journal of Urology·J H Steyn, F W Smith
Dec 2, 2006·Journal of Magnetic Resonance Imaging : JMRI·Akihiro TanimotoSachio Kuribayashi
Feb 11, 2012·European Radiology·Jelle O BarentszUNKNOWN European Society of Urogenital Radiology
Mar 13, 2012·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·Heidi A van VugtMonique J Roobol
Jan 28, 2015·JAMA : the Journal of the American Medical Association·M Minhaj SiddiquiPeter A Pinto
Feb 26, 2015·AJR. American Journal of Roentgenology·Andrew B RosenkrantzSamir S Taneja
Aug 20, 2015·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·M J Pekka RaatikainenGerhardt Hindricks
Oct 3, 2015·European Urology·Jeffrey C WeinrebSadna Verma
Feb 23, 2017·The New England Journal of Medicine·Robert J RussoSteven D Wolff
Sep 22, 2017·RöFo : Fortschritte auf dem Gebiete der Röntgenstrahlen und der Nuklearmedizin·Tim UllrichMichael Quentin
Mar 7, 2018·CNS Drugs·Luca PasquiniMaria Camilla Rossi Espagnet
Mar 20, 2018·The New England Journal of Medicine·Veeru KasivisvanathanUNKNOWN PRECISION Study Group Collaborators

❮ Previous
Next ❯

Citations

May 1, 2019·Der Radiologe·S H PolanecP A T Baltzer
May 16, 2020·Journal of Magnetic Resonance Imaging : JMRI·Nicola SchiedaBaris Turkbey
Aug 10, 2019·Journal of Magnetic Resonance Imaging : JMRI·Rajan T GuptaSadhna Verma
Jan 1, 2019·Memo·Fabian SteinkohlDaniel Junker
Jan 28, 2021·AJR. American Journal of Roentgenology·Renato CuocoloArnaldo Stanzione

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cancer Imaging

Imaging techniques, including CT and MR, have become essential to tumor detection, diagnosis, and monitoring. Here is the latest research on cancer imaging.