Prospective comparison of posterior fossa exploration and stereotactic radiosurgery dorsal root entry zone target as primary surgery for patients with idiopathic trigeminal neuralgia

Neurosurgery
Bruce E Pollock, Kimberly A Schoeberl

Abstract

Trigeminal neuralgia (TN) is the most common facial pain syndrome, with an incidence of approximately 27 per 100,000 patient-years. To prospectively compare facial pain outcomes for patients having either a posterior fossa exploration (PFE) or stereotactic radiosurgery (SRS) as their first surgery for idiopathic TN. Prospective cohort study of 140 patients with idiopathic TN who had either PFE (n = 91) or SRS (n = 49) from June 2001 until September 2007. The groups were similar with regard to sex, pain location, and pain duration. Patients who had SRS were older (67.1 vs 58.2 years; P < .001). The median follow-up after surgery was 38 months. Patients who had PFE more commonly were pain free off medications (84% at 1 year, 77% at 4 years) compared with the SRS patients (66% at 1 year, 56% at 4 years; hazard ratio = 2.5; 95% confidence interval, 1.4-4.6; P = .003). Additional surgery for persistent or recurrent face pain was performed in 14 patients after PFE (15%) compared with 17 patients after SRS (35%; P = .009). Nonbothersome facial numbness occurred more frequently in the SRS group (33% vs 18%; P = .04). No difference was noted in other complications between patients who had PFE (12%) (dysesthetic facial pain, n = 3; cereb...Continue Reading

References

Jan 1, 1989·Journal of Neurosurgery·C B Adams
Sep 1, 1983·Journal of Neurology, Neurosurgery, and Psychiatry·L Leksell
Jan 1, 1993·Stereotactic and Functional Neurosurgery·R W RandM R Fisher
Apr 25, 1996·The New England Journal of Medicine·F G BarkerH D Jho
Jan 1, 1997·Stereotactic and Functional Neurosurgery·K H LeeS S Chung
Jan 1, 1997·Stereotactic and Functional Neurosurgery·A T BergenheimP A Ridderheim
Jul 21, 1999·Journal of Neurosurgery·M R McLaughlinD K Resnick
Jun 23, 2000·International Journal of Radiation Oncology, Biology, Physics·C L RogersB L Speiser
Jul 13, 2000·British Journal of Neurosurgery·H Ryu, S Yamamoto
Jan 9, 2001·Journal of Neurosurgery·S MaesawaL D Lunsford
Jun 21, 2001·Journal of Neurosurgery·D J Skirving, N G Dan
Sep 25, 2001·International Journal of Radiation Oncology, Biology, Physics·J C FlickingerL D Lunsford
Aug 8, 2002·Archives of Neurology·Philip V TheodosopoulosCharles B Wilson
Aug 21, 2002·Journal of Neurosurgery·Bruce E PollockScott L Stafford
Aug 2, 2003·Stereotactic and Functional Neurosurgery·Patric C Blomstedt, A Tommy Bergenheim
Nov 1, 1962·Journal of Neurosurgery·W J GARDNER
Oct 29, 2003·Neurosurgery·Kim J Burchiel
Jun 14, 2005·The Clinical Journal of Pain·Bruce E Pollock, Robert D Ecker
Aug 23, 2005·International Journal of Radiation Oncology, Biology, Physics·Clarissa Febles HensonDavid W Andrews
Dec 7, 2005·Neurosurgery·Gregory M RichardsMinesh P Mehta
Jun 17, 2006·Journal of Neurosurgery·Jean RégisFrançoise Bille-Turc
Apr 22, 2008·Neurosurgery·Alan T VillavicencioJeffrey J Thramann
Oct 3, 2008·Neuropsychiatric Disease and Treatment·Rosanna TarriconeAndrea Casasco
Jan 10, 2009·Journal of Neurosurgery·Shinji MatsudaJunichi Ono
Feb 24, 2009·Journal of Neurosurgery·Jonathan P MillerKim J Burchiel

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Citations

Dec 21, 2011·Current Neurology and Neuroscience Reports·Bruce E Pollock
Sep 13, 2011·Photomedicine and Laser Surgery·Hui-Wen Yang, Yu-Feng Huang
May 2, 2012·Current Opinion in Neurology·Joanna M Zakrzewska, Hugh B Coakham
Apr 8, 2014·Neurologic Clinics·Gaddum Duemani Reddy, Ashwin Viswanathan
Apr 16, 2011·World Neurosurgery·Bruce E Pollock
Dec 25, 2015·Neurología : publicación oficial de la Sociedad Española de Neurología·N Cordero TousG Olivares Granados
Mar 13, 2016·Neurología : publicación oficial de la Sociedad Española de Neurología·F Ruiz-JuretschkeC Fernandez-Carballal
Jan 10, 2012·International Journal of Otolaryngology·Ameer L ElaimyChristopher M Lee
Mar 13, 2014·International Journal of Radiation Oncology, Biology, Physics·John T LucasMichael D Chan
Jun 22, 2016·Neurosurgery Clinics of North America·Amparo Wolf, Douglas Kondziolka
Apr 28, 2018·Journal of Neurosurgery·Constantin TuleascaMarc Levivier
Mar 13, 2019·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·L BendtsenG Cruccu
Jan 16, 2019·Journal of Neurosurgery·Andrew I YangJohn Y K Lee
Jun 6, 2019·Zhurnal voprosy neĭrokhirurgii imeni N. N. Burdenko·A V BervitskiyE V Amelina
Apr 3, 2019·Neurosurgical Review·Alfio SpinaPietro Mortini
Mar 4, 2020·World Neurosurgery: X·Carolina Venda NovaRicheal Ni Riordain
May 30, 2021·Neurología : publicación oficial de la Sociedad Española de Neurología·L Amaya PascasioF Ruiz Juretschke

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