Prospective comparison of the Montreal Cognitive Assessment (MoCA) and the Mini Mental State Examination (MMSE) in geriatric oncology

Journal of Geriatric Oncology
Audrey RambeauFlorence Joly

Abstract

Among the various instruments recommended by the International Society of Geriatric Oncology, the Mini Mental State Examination (MMSE) is the most commonly used cognitive screening test before oncological treatment. Although the Montreal Cognitive Assessment (MoCA) has been shown to be more sensitive than the MMSE in several pathologies, no specific data exist for older patients with cancer. We aimed to compare the proportions of older patients with cancer who had screened positive for cognitive impairment according to the MMSE and MoCA scores obtained during a pretherapeutic geriatric assessment (GA) in oncology. This prospective study was conducted among 66 patients older than 70 years who were candidates for a first-line treatment for either a solid tumor or hematological malignancy. Patients with brain tumor or previously known dementia were ineligible. During GA, cognitive function was assessed using both the MoCA and the MMSE tests administered in a random order. Median age was 78 years. Most patients (n = 43, 65.2%) had a solid tumor. The median scores were 26 [11-30] for MMSE and 24 [8-30] for MoCA. Thirteen (19.7%) and 44 (66.7%) patients were screened positive for cognitive impairment according to MMSE and MoCA scores...Continue Reading

References

Nov 1, 1975·Journal of Psychiatric Research·M F FolsteinP R McHugh
Feb 1, 1991·Journal of the American Geriatrics Society·D Podsiadlo, S Richardson
May 1, 1968·Journal of the American Geriatrics Society·B S LinnL Gurel
Sep 21, 1963·JAMA : the Journal of the American Medical Association·S KATZM W JAFFE
Nov 15, 2003·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Nadine TchenIan F Tannock
Apr 9, 2005·Journal of the American Geriatrics Society·Ziad S NasreddineHoward Chertkow
Feb 25, 2006·The Journals of Gerontology. Series B, Psychological Sciences and Social Sciences·Kathleen InselAurelio Figueredo
Mar 17, 2006·Breast Cancer Research and Treatment·Arti HurriaClifford Hudis
Nov 30, 2007·Movement Disorders : Official Journal of the Movement Disorder Society·Cindy ZadikoffConnie Marras
Oct 20, 2010·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Robert OlsonMichael McKenzie
Dec 24, 2011·Alzheimer Disease and Associated Disorders·Sandra FreitasIsabel Santana
Sep 26, 2012·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Tim A AhlesElizabeth L Ryan
Dec 12, 2012·Cancer Treatment Reviews·Kristy D HodgsonTed Nettelbeck
Feb 12, 2013·Lancet·Andrew CleggKenneth Rockwood
Apr 10, 2014·Cancer Treatment Reviews·Marie LangeFlorence Joly
Apr 29, 2014·Cancer Epidemiology·Tim MathesMichaela Eikermann
May 21, 2014·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Jeanne S MandelblattTim Ahles
Jul 30, 2014·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Hans WildiersArti Hurria
Feb 15, 2015·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Giovanni G ArcuriBruno Gagnon
May 13, 2015·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Brian D GonzalezPaul B Jacobsen
Jun 9, 2015·JAMA Internal Medicine·Kelvin K F TsoiTimothy C Y Kwok
Jul 20, 2016·Breast Cancer Research and Treatment·Philip E LeePaula A Rochon
Dec 13, 2017·Journal of Oncology Practice·Marie Lange, Florence Joly

❮ Previous
Next ❯

Citations

Oct 17, 2019·Annals of Oncology : Official Journal of the European Society for Medical Oncology·M LangeH Castel
Jan 29, 2020·Annals of Oncology : Official Journal of the European Society for Medical Oncology·M LangeH Castel
May 13, 2021·Dementia and Geriatric Cognitive Disorders Extra·Vahid RashediNegin Chehrehnegar

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.