Prospective epidemiological cohort study of reduced risk for incident cataract with vigorous physical activity and cardiorespiratory fitness during a 7-year follow-up.

Investigative Ophthalmology & Visual Science
P T Williams

Abstract

To test whether greater vigorous physical activity (kilometers per week run) and greater cardiorespiratory fitness (10-km race performance in meters per second) reduce the incidence of clinically diagnosed cataract. Prospective cohort study of self-reported clinical diagnosis of cataract in nondiabetic, nonvegetarian, and nonsmoking male (n = 29,025) and female runners (n = 11,967). Incident cataracts were reported by 733 (2.53%) men and 179 (1.50%) women during (mean +/- SE) 7.74 +/- 0.01 and 7.42 +/- 0.02 years of follow-up, respectively. The risk for incident cataract increased with BMI, such that the risk in men > 27.5 kg/m(2) was 88% larger than in men < 20 kg/m(2). Men's cataract risk declined significantly in relation to running distance (P = 0.01), even when adjusted for BMI. Men who ran > or = 64 km/wk had 35% lower risk for cataract than those reporting < 16 km/wk (28% lower risk when adjusted for BMI). In addition, men with greater cardiorespiratory fitness were at significantly less risk for development of cataract than were the least fit men. This result was not accounted for by adjustment for running distance or BMI. Compared with the least fit men, those who ran faster than 4.75 m/s had 50% lower risk for inciden...Continue Reading

Citations

Nov 15, 2011·BMC Ophthalmology·Carol J WaudbyCatherine A McCarty
Apr 7, 2009·Medicine and Science in Sports and Exercise·Paul T Williams
Jul 2, 2009·Medicine and Science in Sports and Exercise·Paul T Williams
Sep 17, 2010·PloS One·Lin LiXiaohua Gong
Jun 11, 2016·Ophthalmology·Sarah FloudJane Green
May 28, 2017·American Journal of Ophthalmology·Myra B McGuinnessRobert P Finger
Aug 11, 2018·Ophthalmic Epidemiology·Arash DelavarElizabeth K Cahoon
Oct 12, 2018·Journal of Sports Sciences·Jesús VeraAmador García-Ramos
Aug 14, 2010·Holistic Nursing Practice·Nancy C Sharts-Hopko
Oct 18, 2016·Journal of Glaucoma·Adam Wylęgała
Jan 1, 2013·Medicine and Science in Sports and Exercise·Paul T Williams
Jun 10, 2017·Journal of Ophthalmology·Joshua D LevinsonJiong Yan
Feb 20, 2020·Ophthalmic Epidemiology·Guillermo F López-SánchezLee Smith
Nov 7, 2019·International Journal of Environmental Research and Public Health·Guillermo F López-SánchezLee Smith
Oct 12, 2018·BMC Ophthalmology·Seung Wan NamTae-Young Chung
Feb 12, 2021·Ophthalmology·Sharon Y L ChuaUNKNOWN UK Biobank Eye and Vision Consortium

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