Prospective evaluation of human chorionic gonadotropin in the differentiation of undescended testes from retractile testes

The Journal of Urology
Oren F MillerG W Kaplan

Abstract

We prospectively evaluated the efficacy of human chorionic gonadotropin (HCG) in the treatment of undescended testis and sought to determine whether HCG assists in the differentiation of undescended testis from retractile testis. Patients with undescended testes were offered HCG. Testis position, laterality and the presence or absence of a hypoplastic scrotum were noted. The same physician (G. W. K.) recorded physical findings prospectively and stated clinical impression of descent. A total of 67 patients with 90 undescended or retractile testes were treated and evaluated with HCG. Of the 64 undescended testes 13 (20%) descended with HCG therapy, with none requiring subsequent surgery. Of the 26 retractile testes 15 (58%) descended with HCG (p <0.001). Based on physical examination, 100% of retractile testes descended if the testis was in the high scrotal position but only 40% descended if the testis was in the superficial pouch or inguinal area. In the undescended testes group no ectopic or nonpalpable testis descended with HCG. Evaluation of HCG with age demonstrated minimal response (15%) to HCG at less than 24 months, and a peak response between ages 2 and 6 years (75%) with response decreasing thereafter. HCG may have a li...Continue Reading

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Citations

Sep 13, 2003·BJU International·G W Kaplan
Oct 13, 2012·Korean journal of urology·Jae Jun BaeSung Kwang Chung
May 28, 2014·Acta Cirúrgica Brasileira·Patricia Magnago AltoéIgor Daniel Loureiro
Oct 17, 2021·International Journal of Urology : Official Journal of the Japanese Urological Association·Shunta HoriKiyohide Fujimoto

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