Prospective evaluation of pain and follow-up results when pre-cooling skin versus buffering lidocaine for upper blepharoplasty

Postgraduate Medicine
Lin Huang

Abstract

To find out whether there is a difference in the incidence of injection pain and other complications using pre-cooling versus the buffered equivalent in upper blepharoplasty. A prospective, randomized study in patients scheduled for primary upper blepharoplasty was performed. Each subject was his/her own control by performing pre-cooling for 2 min before plain lidocaine injection in one eyelid, while the buffered solution injection was used in the other eyelid. Data were collected regarding injection pain, postoperative pain, bleeding, bruising, swelling and scar appearance. Sixty patients participated in this study. Injection pain, checked immediately, revealed a mean operative pain rating of 2.20 ± 0.32 in the eye with pre-cooling versus 2.30 ± 0.35 in the buffered lidocaine (p = 0.074). A statistical difference was observed in postoperative pain after 2-4 h, with the pre-cooling group having a score of 4.00 ± 0.14 versus 4.40 ± 0.30 in the buffered lidocaine group (p = 0.021). The postoperative pain after 24 h was 2.00 ± 0.56 in the pre-cooling group versus 2.30 ± 0.23 in the buffered lidocaine group (p = 0.006). There were no statistical differences between the buffered and unbuffered lidocaine eyes after 2 days or 1 week i...Continue Reading

References

Dec 1, 1976·Anesthesiology·M A Wightman, R W Vaughan
Jul 1, 1992·The Journal of Emergency Medicine·M OrlinskyR Deslauriers
Jan 1, 1992·The Journal of Dermatologic Surgery and Oncology·J M Swinehart
Dec 5, 1966·JAMA : the Journal of the American Medical Association·D I AbramsonM Levin
Dec 1, 1980·Acta Physiologica Scandinavica·H E Torebjörk, J L Ochoa
Mar 10, 1998·Academic Emergency Medicine : Official Journal of the Society for Academic Emergency Medicine·J M BartfieldN Raccio-Robak
Jul 16, 2004·Plastic and Reconstructive Surgery·Lieneke J DraaijersPaul P M van Zuijlen
Jan 13, 2009·Oncology Nursing Forum·Tracy A RueggTammy Lamb
Jan 20, 2011·Facial Plastic Surgery : FPS·Daniel E Rousso, Agata K Brys
Aug 2, 2012·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Mohammed A Al Shahwan

❮ Previous
Next ❯

Citations

Jan 23, 2021·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Oded OhanaWendy W Lee

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.