Prospective evaluation of pain, swelling, and disability from copperhead envenomation

Clinical Toxicology : the Official Journal of the American Academy of Clinical Toxicology and European Association of Poisons Centres and Clinical Toxicologists
Brett RothTiffany Chen

Abstract

In light of the existing controversy regarding antivenin treatment for copperhead envenomation, a more detailed analysis of the disability from this species is needed. Our objective was to prospectively determine the duration of pain, swelling, and functional disability, i.e., residual venom effects, in patients with copperhead envenomation. Patients with venomous snakebite reported to the North Texas Poison Center between April 2009 and November 2011 were assessed. Patients with confirmed envenomations were contacted by a specialist in poison information. Day zero was the day of the bite and verbal phone consent for study enrollment was obtained at that time. The patient (or their guardian) was contacted by phone daily thereafter, and asked to rate their pain, edema/swelling, and disability using the modified DASH and LEFS scales. Patients were followed to resolution of all symptoms or return to baseline. About 104 cases of venomous snakebite were followed; of which 17 were excluded due to being a dry bites (5) or for having insufficient data during follow-up (11) or due to coagulopathy (1). Overall, residual venom effects from copperhead bites for most patients last between 7 and 13 days. Median time to complete pain resoluti...Continue Reading

References

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Citations

Oct 5, 2017·Journal of Medical Toxicology : Official Journal of the American College of Medical Toxicology·Anne-Michelle RuhaUNKNOWN ToxIC Snakebite Study Group
Jan 25, 2020·American Journal of Health-system Pharmacy : AJHP : Official Journal of the American Society of Health-System Pharmacists·Craig CocchioShari Clifton
May 28, 2019·The Western Journal of Emergency Medicine·Caroline E FreiermuthUNKNOWN Copperhead Recovery Workgroup
Oct 28, 2020·Toxins·Manuela B PuccaWuelton M Monteiro
Mar 12, 2021·Clinical Toxicology : the Official Journal of the American Academy of Clinical Toxicology and European Association of Poisons Centres and Clinical Toxicologists·B Z WilsonF M Shirazi

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