PMID: 11931375Apr 5, 2002Paper

Prospective evaluation of platelets prepared by single and random methods during 5 days of storage: aspects related to quality and quantity

Transfusion and Apheresis Science : Official Journal of the World Apheresis Association : Official Journal of the European Society for Haemapheresis
Bekir KocazeybekSelim Erentürk

Abstract

Platelets, which have an important role in hemostatic mechanisms and which were prepared by single and random methods were investigated to measure quantity, and aggregation response during 5 days of storage. The aggregation response and quantitative values of platelet concentrates (PCs), 60 of which were prepared by a single donor method and 62 by a random method were investigated during the 1st, 3rd, and 5th days of storage. The single donor platelets (SDP) were obtained by using the MCS Plus apheresis device and the random donor platelets (RDP) were obtained by two-phase centrifugation in the Heraeus 8500i centrifuge device (during the first phase, platelet rich plasma was obtained then platelet concentrate was obtained from this product) and were stored at 22 degrees C on a circular agitator. In addition, pH, PO2, PCO2, glucose and lactate values were measured in order to evaluate the effects of storage. The aggregation response was measured using adenosine diphosphate (ADP), epinephrine (EPN), collagen (COLL) and ristocetin (RIST). The cell count in mm3 and the total cell count were also measured. The total cell counts and cells in mm3 of the PCs which were prepared by the single donar method on the 1st, 3rd and 5th days, w...Continue Reading

References

Mar 1, 1984·Transfusion·G RockP Tittley
Jul 1, 1996·Cleveland Clinic Journal of Medicine·M A Hussein, G A Hoeltge
Aug 15, 1998·Vox Sanguinis·S Holme

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Citations

Sep 1, 2011·Tissue Engineering. Part C, Methods·Larry C Lasky, Brent Sullenbarger
Jul 3, 2007·Transfusion and Apheresis Science : Official Journal of the World Apheresis Association : Official Journal of the European Society for Haemapheresis·O Meltem AkayZafer Gulbas
May 18, 2004·Vox Sanguinis·D ScheinichenH-A Elsner
Sep 2, 2018·Hematology·Signe SperlingChristian Nielsen

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