PMID: 16633221Apr 25, 2006Paper

Prospective evaluation of preoperative factors associated with successful mitomycin C needling of failed filtration blebs

Journal of Glaucoma
Consuelo Gutiérrez-OrtizMiguel A Teus

Abstract

To study the long-term effectiveness and factors involved in successful needling of failed filtration blebs with mitomycin C (MMC). We conducted a prospective, nonrandomized comparative trial that included 34 consecutive patients (34 eyes) who underwent mitomycin C needling of a failed filtering bleb after trabeculectomy followed by a 0.01 mL injection of mitomycin C (0.2 mg/ml). The success of the needling revision was defined as absolute if the intraocular pressure (IOP) was < 21 mm Hg without antiglaucoma medications and qualified if the IOP was < 21 mm Hg with antiglaucoma medications. Preoperative and perioperative factors were evaluated for an association with postoperative success using Kaplan-Meier survival analysis. The mean follow-up was 14.2 +/- 9.8 months. The mean preoperative IOP was 25.5 +/- 4.4 mm Hg, which decreased to 11.1, 13.4, 15.8, 16.7, 14.9, 14.1, 13.9, and 13 on postoperative day 1, postoperative week 1, and after 1, 3, 6, 9, 12, and 24 months, respectively (P = 0.001 for each comparison). At the final visit, success was absolute in 15 eyes (44.1%) and qualified in 14 eyes (41.2%). The success rates were 90% and 75% at 1 and 2 years, respectively. The success of the needling procedure was highly correla...Continue Reading

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Citations

Feb 3, 2007·The British Journal of Ophthalmology·A J KingJ Moodie
May 25, 2012·Middle East African Journal of Ophthalmology·Heidar AminiRamin Daneshvar
Feb 27, 2015·Journal of Glaucoma·Linda ZhengDavid Wechsler
Dec 18, 2007·Ophthalmology·Alan P Rotchford, Anthony J W King
Sep 1, 2015·Journal of Glaucoma·Evan J AllanMahmoud A Khaimi
Dec 2, 2011·Korean Journal of Ophthalmology : KJO·Ali Bulent Cankaya, Ufuk Elgin
Dec 14, 2016·Indian Journal of Ophthalmology·Maria Tulidowicz-BielakTomasz Żarnowski
May 10, 2017·Journal of Glaucoma·Davinder S Grover, Ronald L Fellman
Dec 29, 2017·Indian Journal of Ophthalmology·Vanita Pathak-Ray, Nikhil Choudhari
Feb 15, 2018·The British Journal of Ophthalmology·Jonathan Y-X L ThanKeith R Martin
Oct 16, 2008·Journal of Glaucoma·Robert M Feldman, Rania R Tabet
May 29, 2019·Journal of Glaucoma·Shunsuke NakakuraYoshiaki Kiuchi
Sep 1, 2017·Journal of Glaucoma·Doaa H Sobeih, Paul R Cotran
Oct 1, 2020·European Journal of Ophthalmology·Consuelo Gutiérrez-Ortiz, Sara Rodrigo-Rey
Feb 26, 2019·European Journal of Ophthalmology·Alessandro RabioloFrancesco Bandello
Jan 20, 2021·Indian Journal of Ophthalmology·G Lizar DemirokÜmit Ekşioğlu
Sep 1, 2011·Journal of Glaucoma·Ehab Mahmoud Ghoneim, Mohamed Abd El Hameed
Mar 16, 2021·European Journal of Ophthalmology·Pornjittra RattanasirivilaiVikas Shankar
Jul 25, 2007·Journal français d'ophtalmologie·A LabbéC Baudouin

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