Prospective evaluation of waist circumference and visceral adipose tissue in patients with chronic kidney disease

American Journal of Nephrology
Claudia M O VelludoLilian Cuppari

Abstract

Waist circumference (WC), a simple anthropometric measure, is associated with visceral adipose tissue (VAT) in cross-sectional studies, and thus has been used as a surrogate marker for VAT. However, associations between changes over time in WC and VAT have not been studied in chronic kidney disease (CKD) patients. This prospective study included 87 nondialysis-dependent CKD patients (54 males, 56.2 +/- 10.4 years, BMI 27.3 +/- 5.1, GFR 35.9 +/- 14.6 ml/min/1.73 m(2)). VAT area was measured by computed tomography (CT) and WC was measured at the umbilicus level at baseline and after 12 months. Changes in WC correlated significantly but weakly with changes in VAT (r = 0.26, p = 0.016), likely due to a substantially smaller change in WC compared to changes in VAT. This was also reflected by a kappa coefficient of 0.26, i.e. indicative of poor agreement between WC and CT measurements in regards to quantification of changes in VAT. Likewise, the receiver operating characteristic curve analysis identified WC as poor predictor of changes in VAT (area under the curve = 0.62). Anthropometric measurement of WC is poorly correlated with changes in VAT measured by CT in nondialysis-dependent CKD patients. Therefore, caution should be taken ...Continue Reading

Citations

Jul 31, 2012·Nutrition, Metabolism, and Cardiovascular Diseases : NMCD·M A KamimuraL Cuppari
Sep 29, 2011·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Ana Paula BazanelliLilian Cuppari
Jul 9, 2013·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Antonio Carlos CordeiroJuan Jesús Carrero
Jan 23, 2014·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Flavia BariaLilian Cuppari
Jun 6, 2013·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Peter StenvinkelCarmine Zoccali
Sep 24, 2015·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·Ding ZhaoBo Shen
Mar 4, 2014·European Journal of Clinical Investigation·Maryam BarzinFereidoun Azizi
Aug 5, 2014·Seminars in Dialysis·Juan Jesús Carrero, Carla Maria Avesani
May 24, 2011·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Holly KramerWilliam McClellan
Jun 12, 2009·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·John MunkhaugenStein Hallan
Jun 7, 2017·The British Journal of Nutrition·Ana Catarina M CastroMaria A Kamimura
Sep 29, 2011·Circulation·Marc-Andre CornierUNKNOWN Council on the Kidney in Cardiovascular Disease, and Stroke Council
Oct 12, 2013·Journal of the American Society of Nephrology : JASN·Peter StenvinkelT Alp Ikizler
Sep 27, 2012·Current Opinion in Nephrology and Hypertension·Carmine ZoccaliFrancesca Mallamaci
Jun 18, 2016·Medicine and Science in Sports and Exercise·Dirk VissersJan Taeymans

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