Prospective External Validation of Three Preoperative Risk Scores for Prediction of New Onset Atrial Fibrillation After Cardiac Surgery

Anesthesia and Analgesia
Matthew J CameronJean-Yves Dupuis

Abstract

Postoperative atrial fibrillation (POAF) is associated with early and late morbidity and mortality of cardiac surgical patients. Prophylactic treatment of atrial fibrillation (AF) has been recommended to improve outcome in cardiac surgical patients at high risk of developing POAF. Reliable models for prediction of POAF are needed to achieve that goal. This study attempted to externally validate 3 risk models proposed for preoperative prediction of POAF in cardiac surgical patients: the POAF score, the CHA2DS2-VASc score, and the Atrial Fibrillation Risk Index. This was a prospective cohort study of 1416 adult patients who underwent nonemergent coronary artery bypass graft and/or valve surgery in a single cardiac surgical center between February 2014 and September 2015. A risk score for each of the 3 prediction models was calculated in each patient. All patients were followed for up to 2 weeks, or until hospital discharge, to observe the primary outcome of new onset AF requiring treatment. Discrimination was assessed using receiver operating characteristic curves. Calibration was assessed using the Pearson χ goodness-of-fit test and calibration plots. Utility of the score to implement AF prophylaxis based on the risk of POAF, in...Continue Reading

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Citations

Dec 19, 2017·Anesthesia and Analgesia·Anis John KadadoJoseph G Akar
Apr 13, 2018·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·Nathan H WaldronJoseph P Mathew
Nov 15, 2019·Circulation. Cardiovascular Quality and Outcomes·Bryan MaMatthew T James
Sep 11, 2019·American Journal of Cardiovascular Drugs : Drugs, Devices, and Other Interventions·Yousef RezaeiSaeid Hosseini
Nov 9, 2019·Current Anesthesiology Reports·Peter S BurrageBen O'Brien
Jan 7, 2021·European Journal of Internal Medicine·Alessandro AlbiniGiuseppe Boriani
Feb 1, 2021·Cardiac Electrophysiology Clinics·Martin AguilarStanley Nattel
Jul 17, 2019·The Journal of Thoracic and Cardiovascular Surgery·Lucrecia María BurgosDaniel Navia
Jul 20, 2021·The Journal of Thoracic and Cardiovascular Surgery·Yisi LiuHaibo Zhao
May 12, 2021·Thrombosis and Haemostasis·Oana Maria Cole

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