Prospective forecasts of annual dengue hemorrhagic fever incidence in Thailand, 2010-2014

Proceedings of the National Academy of Sciences of the United States of America
Stephen A LauerNicholas G Reich

Abstract

Dengue hemorrhagic fever (DHF), a severe manifestation of dengue viral infection that can cause severe bleeding, organ impairment, and even death, affects between 15,000 and 105,000 people each year in Thailand. While all Thai provinces experience at least one DHF case most years, the distribution of cases shifts regionally from year to year. Accurately forecasting where DHF outbreaks occur before the dengue season could help public health officials prioritize public health activities. We develop statistical models that use biologically plausible covariates, observed by April each year, to forecast the cumulative DHF incidence for the remainder of the year. We perform cross-validation during the training phase (2000-2009) to select the covariates for these models. A parsimonious model based on preseason incidence outperforms the 10-y median for 65% of province-level annual forecasts, reduces the mean absolute error by 19%, and successfully forecasts outbreaks (area under the receiver operating characteristic curve = 0.84) over the testing period (2010-2014). We find that functions of past incidence contribute most strongly to model performance, whereas the importance of environmental covariates varies regionally. This work illu...Continue Reading

References

Jan 1, 1988·The American Journal of Tropical Medicine and Hygiene·D S BurkeR M Scott
Sep 30, 1998·Lancet·J G Rigau-PérezA V Vorndam
Sep 13, 2002·Tropical Medicine & International Health : TM & IH·Maria da Glória TeixeiraSandy Cairncross
Jul 27, 2006·Proceedings of the National Academy of Sciences of the United States of America·Helen J Wearing, Pejman Rohani
Sep 13, 2006·Proceedings of the National Academy of Sciences of the United States of America·B AdamsM Boots
Feb 18, 2009·PLoS Neglected Tropical Diseases·Michael A JohanssonGregory E Glass
Dec 5, 2012·PLoS Neglected Tropical Diseases·Yien Ling HiiJoacim Rocklöv
Apr 9, 2013·Nature·Samir BhattSimon I Hay
Jul 5, 2013·Journal of the Royal Society, Interface·Nicholas G ReichDerek A T Cummings
Aug 21, 2013·The American Journal of Tropical Medicine and Hygiene·Karen M CampbellThomas W Scott
Feb 6, 2016·PLoS Neglected Tropical Diseases·Vinicius M FavaUNKNOWN Canadian Lrrk2 in Inflammation Team (CLINT)
Feb 6, 2016·PLoS Neglected Tropical Diseases·Brett M ForsheySteven T Stoddard
Feb 15, 2016·The Lancet Infectious Diseases·Jeffrey D StanawayChristopher J L Murray
Mar 18, 2016·The Journal of Infectious Diseases·Jesse J WaggonerEva Harris
Jun 16, 2016·PLoS Neglected Tropical Diseases·Nicholas G ReichJustin Lessler
Oct 14, 2016·Journal of the Royal Society, Interface·Teresa K YamanaJeffrey Shaman
Feb 1, 2017·The American Statistician·Nicholas G ReichDerek A T Cummings
Sep 15, 2017·Statistics in Medicine·Evan L RayNicholas G Reich
Dec 8, 2017·BioRxiv : the Preprint Server for Biology·J. H. HuberErin A Mordecai

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Citations

Mar 4, 2020·The American Journal of Tropical Medicine and Hygiene·Hisham Ahmed ImadTatsuo Shioda
Sep 3, 2019·BMC Medicine·Mahmood AkhtarLauren M Gardner
Nov 20, 2019·Emerging Infectious Diseases·Anthony CousienArnaud Tarantola
Aug 17, 2020·Journal of Physiological Anthropology·Narinderjeet KaurKamruddin Ahmed
Oct 30, 2020·PLoS Neglected Tropical Diseases·Jue Tao LimAlex R Cook
Jan 15, 2021·Scientific Reports·Mathew V KiangCaroline O Buckee
Mar 5, 2021·PLoS Medicine·Felipe J Colón-GonzálezRachel Lowe
Apr 6, 2021·Journal of Healthcare Engineering·Bilal KhanMarwan Mahmoud
May 22, 2021·PLoS Neglected Tropical Diseases·Lauren A CastroSara Y Del Valle

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