PMID: 8588567Dec 1, 1995Paper

Prospective monitoring of early fetal loss and clinical spontaneous abortion among female semiconductor workers

American Journal of Industrial Medicine
Brenda EskenaziM B Schenker

Abstract

Women who work in silicon wafer fabrication rooms (fabs) have been reported to have an increased risk of spontaneous abortion (SAB). Although previous studies have included only clinically recognized SABs, more than two-thirds of SABs may be clinically unrecognized. To determine whether fab work is associated with SAB, we recruited 152 fab and 251 nonfab workers, who collected urine samples for a 6-month period. Samples were analyzed by immunoradiometric assay for the presence of human chorionic gonadotropin to detect early fetal losses. Approximately 63% of fab and 46% of nonfab pregnancies ended in SAB [adjusted relative risk (RR) = 1.25; 95% confidence interval (CI) = 0.63-1.76]. Similar RR were seen for women who worked in dopant and thin-film processes (adjusted RR = 1.30; 95% CI = 0.51-1.96) or in masking (adjusted RR = 1.30; 95% CI = 0.59-1.84). The four pregnancies among women who worked with ethylene-based glycol ethers ended in SAB.

References

Jul 28, 1988·The New England Journal of Medicine·A J WilcoxB C Nisula
Sep 13, 1980·Lancet·J F MillerA Sykes
May 21, 1983·Lancet·P G WhittakerT Lind
Dec 1, 1995·American Journal of Industrial Medicine·S K HammondM B Schenker
Dec 1, 1995·American Journal of Industrial Medicine·B L LasleyJ W Overstreet
Dec 1, 1995·American Journal of Industrial Medicine·B EskenaziM B Schenker

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Citations

Jun 5, 2003·Environmental Health Perspectives·Brenda EskenaziDonald G Patterson
Jul 27, 2007·International Archives of Occupational and Environmental Health·Robert WinkerHugo W Rüdiger
May 30, 2008·International Journal of Occupational and Environmental Health·Ching-Chun LinPau-Chung Chen
May 10, 2008·Occupational Medicine·Ching-Chun LinPau-Chung Chen
Apr 19, 2012·Birth Defects Research. Part A, Clinical and Molecular Teratology·Lyndsay Ammon AvalosDe-Kun Li
Jul 23, 2013·Nicotine & Tobacco Research : Official Journal of the Society for Research on Nicotine and Tobacco·David LevyMichele Bloch
Jul 8, 2014·International Journal of Occupational and Environmental Health·Myoung-Hee KimDomyung Paek
Dec 1, 1995·American Journal of Industrial Medicine·B L LasleyJ W Overstreet
Dec 1, 1995·American Journal of Industrial Medicine·M B SchenkerS H Swan
Dec 1, 1995·American Journal of Industrial Medicine·B EskenaziM B Schenker
Aug 29, 2014·Human Reproduction·K J SapraG M Buck Louis
Feb 26, 1999·International Journal of Occupational and Environmental Health·B FowlerD T Teitelbaum
May 20, 1999·International Journal of Occupational and Environmental Health·R C Elliott
Oct 3, 1999·American Journal of Industrial Medicine·B FowlerD T Teitelbaum
Oct 7, 2008·Reproductive Sciences·Karen Perry StillermanTracey J Woodruff
Feb 13, 2014·American Journal of Epidemiology·Beth L PinelesJonathan M Samet
Jun 11, 1999·American Journal of Industrial Medicine·M L Lindbohm
Oct 19, 2017·Annals of Occupational and Environmental Medicine·Heechan KimSangchul Roh
Nov 27, 2019·International Journal of Environmental Research and Public Health·Kyungsik KimSue K Park
Jun 14, 2000·Critical Reviews in Toxicology·G Johanson
Jul 6, 2018·Reviews on Environmental Health·Alexandra GrippoLina Mu
Jun 3, 2021·International Journal of Environmental Research and Public Health·Fumei GaoKun Tang

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