Prospective, Randomized, Controlled Comparison of Bupivacaine versus Liposomal Bupivacaine for Pain Management after Unilateral Delayed Deep Inferior Epigastric Perforator Free Flap Reconstruction

Plastic and Reconstructive Surgery
James GatherwrightRisal Djohan

Abstract

Effective postsurgical analgesia is a critical aspect of patient recovery. The goal of this prospective, randomized, controlled, blinded study was to examine the effect that liposomal bupivacaine delivered by means of a transversus abdominis plane block has on pain control in women undergoing unilateral deep inferior epigastric perforator flap reconstruction. Institutional review board approval was granted for this prospective study. Patients were eligible if they were undergoing unilateral, delayed deep inferior epigastric perforator flap reconstruction. Patients were randomized to one of three groups: liposomal bupivacaine transversus abdominis plane block, or bupivacaine pain pump. Charts were reviewed for demographics, length of stay, and postoperative narcotic use. There were eight patients in the liposomal bupivacaine and bupivacaine transversus abdominis plane block groups and five patients in the pain pump group. A retrospective cohort of six patients who did not receive any intervention was included. Patients who received a liposomal bupivacaine transversus abdominis plane block used statistically significantly less intravenous and total postoperative narcotics in milligrams and milligrams per kilogram per day compared...Continue Reading

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Sep 28, 2016·Plastic and Reconstructive Surgery·Krishna S VyasHenry C Vasconez

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Citations

Jan 28, 2020·Plastic and Reconstructive Surgery·Fereydoun Don ParsaAlan A Parsa
Jul 26, 2019·Annals of Surgical Oncology·Betty FanStephen R Grobmyer
Jan 18, 2020·Nanoscale Research Letters·Yumiao HeChao Ma
May 19, 2021·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·A GilmourL Martin
Jun 22, 2021·Anesthesiology and Pain Medicine·Ariel Clare JohnsonDavid W Mathes
Jul 30, 2021·Current Opinion in Anaesthesiology·Leander MancelAna M Lopez
Sep 10, 2021·The Annals of Pharmacotherapy·Atul DilawriSneha Shah
Oct 28, 2021·Plastic and Reconstructive Surgery·Nicholas T HaddockSumeet S Teotia

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