Prospective randomized trial of moderately strenuous aerobic exercise after an implantable cardioverter defibrillator

Circulation
Cynthia M DoughertyPeter J Kudenchuk

Abstract

Despite its salutary effects on health, aerobic exercise is often avoided after receipt of an implantable cardioverter defibrillator (ICD) because of fears that exercise may provoke acute arrhythmias. We prospectively evaluated the effects of a home aerobic exercise training and maintenance program (EX) on aerobic performance, ICD shocks, and hospitalizations exclusively in ICD recipients. A total of 160 patients (124 men and 36 women) were randomly assigned who had an ICD for primary (43%) or secondary (57%) prevention to EX or usual care (UC). The primary outcome was peak oxygen consumption, measured with cardiopulmonary exercise testing at baseline and 8 and 24 weeks. EX consisted of 8 weeks of home walking for 1 h/d, 5 d/wk at 60% to 80% of heart rate reserve, followed by 16 weeks of maintenance home walking for 150 min/wk. Adherence to EX was determined from exercise logs, ambulatory heart rate recordings of exercise, and weekly telephone contacts. Patients assigned to UC received no exercise directives and were monitored by monthly telephone contact. Adverse events were identified by ICD interrogations, patient reports, and medical charts. ICD recipients averaged 55±12 years and mean ejection fraction of 40.6±15.7; all we...Continue Reading

Associated Clinical Trials

Aug 29, 2007·Cindy Dougherty

References

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Citations

Nov 10, 2015·Pacing and Clinical Electrophysiology : PACE·Cynthia M DoughertyWilliam L Haskell
Apr 28, 2016·Pacing and Clinical Electrophysiology : PACE·Antonis S Manolis, Antonis A Manolis
Feb 2, 2019·The Cochrane Database of Systematic Reviews·Carolina Santiago de Araújo PioSherry L Grace
Feb 13, 2019·The Cochrane Database of Systematic Reviews·Kim M NielsenSelina K Berg
Aug 10, 2019·Journal of Cardiopulmonary Rehabilitation and Prevention·Daniel A SteinhausDaniel B Kramer
Aug 10, 2019·Journal of Cardiopulmonary Rehabilitation and Prevention·Cynthia M DoughertyRobb W Glenny
Feb 22, 2018·Journal of Cardiopulmonary Rehabilitation and Prevention·Afnan Hamad AlswyanCynthia M Dougherty
Oct 4, 2017·Wiener medizinische Wochenschrift·Johann Altenberger
Feb 27, 2021·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Roberto F E PedrettiDominique Hansen
Nov 28, 2017·Cardiac Electrophysiology Clinics·Gourg Atteya, Rachel Lampert
Sep 18, 2020·Journal of Cardiovascular Medicine·Luigi SciarraSilvio Romano

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