Prospective study confirms that bronchiolitis in early infancy increases the risk of reduced lung function at 10-13 years of age

Acta Paediatrica
Riikka RiikonenMatti Korppi

Abstract

This study evaluated children hospitalised for bronchiolitis at less than six months of age to see if they had reduced lung function in early adolescence. We have prospectively followed 166 children hospitalised for infant bronchiolitis in 2001-2004 at Tampere University Hospital, Finland. At 10-13 years of age, flow-volume spirometry was measured in 89 cases and 108 controls without infant bronchiolitis from the local population register. Parameters of flow-volume spirometry before and after bronchodilation were analysed. Forced expiratory volume in one second/forced vital capacity (FEV1/FVC) after bronchodilation was lower in cases than controls. FEV1 was pathological - under the 5th percentile of the national references - in 25% of cases and 12% of controls (p = 0.020) before bronchodilation and in 18% of cases and 5% of controls (p = 0.003) after bronchodilation. FEV1/FVC was pathological in 25% of cases and 13% of controls (p = 0.034) before bronchodilation. Logistic regression, adjusted for current asthma and maternal smoking, showed that infant bronchiolitis was associated with pathological FEV1 before (odds ratio 2.4) and after (odds ratio 4.4) bronchodilation. The result was similar for positive respiratory syncytial v...Continue Reading

References

Oct 1, 1994·Archives of Pediatrics & Adolescent Medicine·M KorppiK Launiala
Apr 1, 1997·Archives of Disease in Childhood·V NobleA D Milner
Apr 1, 1997·Acta Paediatrica·G WennergrenS Redfors
Jan 18, 2003·The Journal of Allergy and Clinical Immunology·Anne Kotaniemi-SyrjänenMatti Korppi
Nov 2, 2004·American Journal of Respiratory and Critical Care Medicine·Nele SigursBengt Kjellman
Aug 2, 2005·The European Respiratory Journal·M R MillerUNKNOWN ATS/ERS Task Force
Aug 6, 2005·Pediatric Pulmonology·Mari K HyvärinenMatti O Korppi
Oct 4, 2006·Pediatrics·UNKNOWN American Academy of Pediatrics Subcommittee on Diagnosis and Management of Bronchiolitis
Feb 19, 2008·Paediatric Respiratory Reviews·Louis I Landau
Jan 16, 2009·Pediatrics International : Official Journal of the Japan Pediatric Society·Anne Kotaniemi-SyrjänenMatti Korppi
Nov 4, 2010·The Pediatric Infectious Disease Journal·Kirsi NuolivirtaMerja Helminen
May 4, 2011·Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology·Tuomas Jartti, Matti Korppi
Jun 28, 2011·The European Respiratory Journal·P KoponenM Korppi
Mar 23, 2012·Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology·Ingvild B MikalsenKnut Øymar
Mar 29, 2014·Pediatric Pulmonology·Eero LauhkonenMatti Korppi
Oct 29, 2014·Pediatrics·Shawn L RalstonSinsi Hernandez-Cancio
Apr 23, 2016·Chest·Leah JayesUNKNOWN Tobacco Control Committee of the European Respiratory Society
Nov 7, 2017·Allergy·S TörmänenK Nuolivirta

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Citations

Apr 6, 2020·Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology·Matti Korppi, Riikka Riikonen
Sep 28, 2018·MMW Fortschritte der Medizin·D Reinhardt
May 3, 2019·ERJ Open Research·Raffaella NennaJonathan Grigg
Oct 25, 2020·Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology·Maleewan KitcharoensakkulMario Castro
Jul 13, 2020·Pediatrics International : Official Journal of the Japan Pediatric Society·Eero LauhkonenMatti Korppi
May 2, 2021·Acta Paediatrica·Matti Korppi, Riikka Riikonen
Apr 21, 2021·Pediatrics International : Official Journal of the Japan Pediatric Society·Sari TörmänenEero Lauhkonen
Aug 1, 2021·Respiratory Medicine·Riikka RiikonenEero Lauhkonen

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