PROSPECTIVE STUDY OF ASPIRIN FOR THROMBOEMBOLISM PROPHYLAXIS IN TOTAL HIP ARTHROPLASTY

Acta ortopedica brasileira
Raul Carneiro LinsFlávio Kreimer

Abstract

To evaluate the effectiveness of aspirin as prophylaxis for deep venous thrombosis (DVT) in patients undergoing total hip arthroplasty (THA), and to analyze the incidence of bleeding during the post-operative period. This prospective study carried out in 2017 consisted of 37 patients indicated for THA with high risk for DVT. Immediately after the procedure, aspirin, elastic compression socks and early deambulation were initiated. Doppler ultrasound was performed in the legs 6 days and 6 weeks post-procedure to rule out venous thromboembolism. Hematometric variables and clinical criteria were used to detect bleeding. The incidence of VTE (venous thromboembolism) 6 days post-procedure was 21.6%. By 6 weeks post-procedure, it dropped to 8.1%, (p = 0.102). Only 2.7% were diagnosed with VTE, 6 days and also 6 weeks post-procedure. Within the immediate postoperative period, hemoglobin was lower (p < 0.001), in contrast to 6 weeks after surgery, when it returned to baseline levels. Aspirin was an effective chemical prophylaxis for venous thromboembolism in high-risk patients who underwent THA. There was no clinical record of postoperative bleeding and hematometric levels suggested that there was no chronic bleeding. Level of Evidence ...Continue Reading

References

Jul 1, 1978·Medicine·L GoldmanE E Slater
Oct 11, 1992·Chest·G P ClagettH B Wheeler
Aug 2, 1969·Lancet·V V KakkarM B Clarke
Aug 1, 1994·The Journal of Bone and Joint Surgery. American Volume·J R Lieberman, W H Geerts
Jul 29, 1998·Archives of Internal Medicine·R H WhiteW Bargar
Sep 6, 2005·The Journal of Bone and Joint Surgery. American Volume·Jay R Lieberman, Wellington K Hsu
Oct 11, 2007·The Journal of Arthroplasty·Javad ParviziRichard H Rothman
May 3, 2008·The Journal of Bone and Joint Surgery. British Volume·J DanielD J W McMinn
Jan 1, 2007·Journal of Long-term Effects of Medical Implants·Javad ParviziChelsea Dalsey
Feb 22, 2012·Hip International : the Journal of Clinical and Experimental Research on Hip Pathology and Therapy·Aswin ChariHemant Pandit
Mar 1, 2012·Hip International : the Journal of Clinical and Experimental Research on Hip Pathology and Therapy·Alexander L AquilinaAshley W Blom
Jul 3, 2013·Clinical Orthopaedics and Related Research·Ibrahim J RaphaelJavad Parvizi
Oct 19, 2016·The Journal of Arthroplasty·Vincent V G AnWarwick J M Bruce

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Methods Mentioned

BETA
Total Hip Arthroplasty
total hip artrhoplasty

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Excel
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