Prospective study of health-related quality of life after Roux-en-Y bypass surgery for morbid obesity

The British Journal of Surgery
C-Y ChangJ-D Wang

Abstract

The aim of this study was to evaluate the effects of Roux-en-Y gastric bypass for morbid obesity on health-related quality of life (QOL) during the first year of follow-up. The World Health Organization Quality of Life-Brief (WHOQOL-BREF) was administered 1 month before operation, and at 1, 3, 6 and 12 months after surgery. Body mass index, co-morbidities and operation-related complications were measured at these times. A mixed-effect model was constructed to analyse repeated measurements and determine the relationships between body mass index, WHOQOL-BREF scores and other variables. A total of 102 patients were enrolled. The mixed-effect model showed that the physical, psychological and social domains improved after bariatric surgery, with simultaneous reduction in weight and improvement in co-morbidities. There was a dip in scores in physical and psychological domains 3-6 months after surgery, significantly related to complications. All patients gradually improved between 6 and 12 months after surgery, reaching levels similar to those of healthy subjects. Health-related QOL improved dramatically after bariatric surgery, dipped slightly between 3 and 6 months, and improved again up to the end of the first year.

References

Apr 1, 1993·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation
Oct 12, 2001·Obesity Surgery·J GlinskiE Goodman
Mar 12, 2002·Journal of the American Academy of Child and Adolescent Psychiatry·Jeffrey M HalperinJeffrey H Newcorn
Apr 11, 2003·Archives of Surgery·Edward H Livingston, Aaron S Fink
Sep 19, 2003·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·Chiun HsuJih-Luh Tang
Oct 15, 2003·Archives of Internal Medicine·Roland Sturm
Oct 28, 2003·The Journal of Nursing Research : JNR·Meei-Horng YangKwua-Yun Wang
Mar 12, 2004·The New England Journal of Medicine·Robert Steinbrook
Oct 14, 2004·JAMA : the Journal of the American Medical Association·Henry BuchwaldKaren Schoelles
Mar 26, 2005·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·Ping-Chuan HsiungJung-Der Wang
Apr 6, 2005·Annals of Internal Medicine·Melinda A MaggardPaul G Shekelle
Jun 28, 2005·Obesity Surgery·Wei-Jei Lee, Weu Wang
Aug 3, 2005·The Surgical Clinics of North America·Zhaoping LiDavid Heber
Dec 6, 2005·International Journal of Epidemiology·Andrew M Prentice
Jan 18, 2006·Archives of Surgery·Matthew M DavisMichael D Cabana
Apr 6, 2006·JAMA : the Journal of the American Medical Association·Cynthia L OgdenKatherine M Flegal
May 4, 2006·The British Journal of Surgery·M SuterV Giusti
Aug 11, 2006·Obesity·Sherrie Selwyn DelinskyG Terence Wilson
Oct 13, 2006·Health and Quality of Life Outcomes·UNKNOWN U.S. Department of Health and Human Services FDA Center for Drug Evaluation and ResearchUNKNOWN U.S. Department of Health and Human Services FDA Center for Devices and Radiological Health
May 15, 2007·Gastroenterology·Katherine A Elder, Bruce M Wolfe
Mar 1, 2008·Obesity Reviews : an Official Journal of the International Association for the Study of Obesity·K-C Huang

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Citations

Jun 20, 2014·World Journal of Gastroenterology : WJG·Po-Jui YuYi-Chih Lee
Apr 1, 2014·Obesity Surgery·Ramona BurgmerStephan Herpertz
Apr 18, 2014·Current Psychiatry Reports·Kristen VotrubaBruno Giordani
May 23, 2012·Surgery for Obesity and Related Diseases : Official Journal of the American Society for Bariatric Surgery·Seiichi KitahamaEmma J Patterson
Dec 3, 2014·Obesity Reviews : an Official Journal of the International Association for the Study of Obesity·J C HopkinsUNKNOWN By-Band Trial Management Group
Jun 23, 2015·Obesity Reviews : an Official Journal of the International Association for the Study of Obesity·N LindekildeA Jones
Dec 3, 2014·Surgery for Obesity and Related Diseases : Official Journal of the American Society for Bariatric Surgery·Vasileios CharalampakisJohn Melissas
Aug 3, 2014·Obesity Surgery·Vasileios EfthymiouKonstantinos Assimakopoulos
Oct 25, 2016·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Vasileios CharalampakisRishi Singhal
Dec 15, 2010·Current Opinion in Gastroenterology·Zoltan PatakyAlain Golay
Nov 16, 2016·Health and Quality of Life Outcomes·Chi-Yang ChangJaw-Town Lin
Mar 31, 2012·Arquivos brasileiros de endocrinologia e metabologia·Cristina KhawaliSandra R G Ferreira
Mar 1, 2017·Porto Biomedical Journal·Gil Filipe Ramada FariaDonald C Simonson

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