PMID: 9171746May 1, 1997Paper

Prospective study of hepatobiliary scintigraphy and endoscopic cholangiography for the detection of early biliary complications after orthotopic liver transplantation

The British Journal of Surgery
T R KurzawinskiB R Davidson

Abstract

Biliary complications are a significant cause of morbidity and death after orthotopic liver transplantation (OLT). This study was a prospective evaluation of endoscopic retrograde cholangiography (ERC) and hepatobiliary scintigraphy (HBS), using 99mTc Mebrofenin, to detect early biliary complications following OLT. One hundred consecutive patients who had OLT with a biliary duct-to-duct anastomosis were studied. Of these, 67 had both ERC and HBS performed within 30 days of OLT. Sensitivity, specificity and diagnostic accuracy of HBS in identifying biliary leak or stricture was calculated. Of the 67 cholangiographies performed 45 were normal. In 22 patients there was radiological evidence of a leak (n = 14) or stricture (n = 8) which required further intervention in nine and four patients respectively. The sensitivity and specificity of scintigraphy for the detection of biliary leak after transplantation was 50 and 79 per cent and for biliary stricture 62 and 64 per cent respectively. No patient with normal scintigraphy required biliary intervention. Only six of 14 patients with biliary leaks and two of 20 with strictures suggested by scintigraphy required intervention. If both ERC and HBS reported leak or stricture, the interve...Continue Reading

References

May 1, 1992·American Journal of Surgery·R R LopezC W Pinson
Jan 1, 1988·Annals of Surgery·J W MarshT E Starzl
Sep 1, 1988·HPB Surgery : a World Journal of Hepatic, Pancreatic and Biliary Surgery·G BelliM L Santangelo
Jan 1, 1987·Transplantation·J LerutT E Starzl
Jun 1, 1987·AJR. American Journal of Roentgenology·J G LetourneauM P Frick
Jan 1, 1985·AJR. American Journal of Roentgenology·A B ZajkoT E Starzl
Jan 1, 1996·Transplant International : Official Journal of the European Society for Organ Transplantation·V DistanteK Rolles
Oct 1, 1996·European Journal of Gastroenterology & Hepatology·B MacfarlaneA K Burroughs

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Citations

Mar 17, 2000·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·B R DavidsonK Rolles
Dec 2, 2006·Journal of Hepato-biliary-pancreatic Surgery·Seigo NishidaAndreas G Tzakis
Sep 12, 2000·Current Gastroenterology Reports·E Corazziari
Mar 7, 2002·Current Treatment Options in Gastroenterology·Sanjay Jagannath, Anthony N. Kalloo
Mar 12, 1999·The Surgical Clinics of North America·G V MazariegosD J Kramer
Feb 15, 2000·The British Journal of Surgery·S K MathurS Shikare
Feb 2, 2012·Seminars in Nuclear Medicine·Roelof J BenninkThomas M van Gulik
May 11, 2002·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Sudeep R ShahBrian R Davidson
Dec 1, 2004·Seminars in Interventional Radiology·Nishita KotharyRichard D Shlansky-Goldberg
Jun 17, 2011·World Journal of Gastroenterology : WJG·Yu Jin KimChoon Hyuck David Kwon
Aug 5, 2011·Gut and Liver·Choong Heon Ryu, Sung Koo Lee
May 31, 2014·World Journal of Gastroenterology : WJG·Yu-Fan ChengChao-Long Chen
Nov 27, 2008·Pediatric Transplantation·Rebecca C ConcannonMichael O Stormon
Aug 27, 2016·International Journal of Molecular Imaging·Manuel EckenschwillerFrank Grünwald
May 30, 2008·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Sharad SharmaNicolas Jabbour
Jul 22, 2005·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Bijan EghtesadJohn Fung
Jun 20, 2006·Scandinavian Journal of Gastroenterology. Supplement·Robert C VerdonkElizabeth B Haagsma
Apr 23, 2015·Clinical Nuclear Medicine·Lesley FlyntFeng Qing

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