Prospects for development and use of recombinant deoxyribonucleic acid techniques with ruminal bacteria

Journal of Dairy Science
C J Smith, R B Hespell

Abstract

Over the last decade, developments in recombinant deoxyribonucleic acid techniques and molecular biology have revolutionized bacterial genetics, creating vast, new potential uses of bacteria (as well as animal and plant cells) that were not even considered previously. Bacterial production of hormones is but one example. With bacterial species with well developed genetic systems, such as Escherichia coli, it is now possible genetically to "design" or "engineer" bacterial strains having specific characteristics. One reasonable future approach toward improvement of animal agriculture would be manipulation of the rumen ecosystem via the use of genetically modified ruminal bacteria, but significant obstacles exist with this approach. Genetic systems of ruminal and of anaerobic bacteria of the mammalian gastrointestinal tract, in general, have not been studied and are largely unknown. In this paper, the various criteria for possible establishment of recombinant deoxyribonucleic acid systems in ruminal bacteria are outlined. Secondly, applications for utilizing genetically engineered ruminal bacteria to control digestion of specific feedstuffs, to regulate specific fermentation products, and to control growth of specific bacterial spe...Continue Reading

References

Jan 5, 1979·Molecular & General Genetics : MGG·S Chang, S N Cohen
Jan 1, 1979·The Journal of Infectious Diseases·G PriviteraM Sebald
Jul 1, 1979·Proceedings of the National Academy of Sciences of the United States of America·R T FraleyS Kaplan
Jan 1, 1979·The Journal of Infectious Diseases·F P TallyM H Malamy
Apr 1, 1979·Plasmid·R A WelchF L Macrina
Jul 14, 1977·Nature·N A Mitchison
May 1, 1977·Applied and Environmental Microbiology·M A WoznyW E Moore
Aug 1, 1972·Proceedings of the National Academy of Sciences of the United States of America·S N CohenL Hsu
Jan 1, 1969·Annual Review of Microbiology·R L Anderson, W A Wood
Jul 1, 1981·Applied and Environmental Microbiology·C J SmithM P Bryant
May 1, 1981·Canadian Journal of Microbiology·D Groleau, C W Forsberg
Jul 1, 1981·Applied and Environmental Microbiology·B R GenthnerM P Bryant
Oct 1, 1981·Journal of Clinical Microbiology·B L WallaceM Rogolsky
Jan 15, 1981·Nature·T G Cooper
Jan 1, 1982·Antimicrobial Agents and Chemotherapy·T D MaysF L Macrina
Jun 1, 1981·Antimicrobial Agents and Chemotherapy·C J SmithF L Macrina
Feb 1, 1982·Applied and Environmental Microbiology·R M Teather

Citations

Sep 1, 1987·The Proceedings of the Nutrition Society·R B Hespell
Jan 1, 1993·Archiv für Tierernährung·V KmetR J Wallace
Jan 1, 1996·Critical Reviews in Microbiology·S C RickeD J Nisbet
Apr 1, 1993·The Journal of Applied Bacteriology·R J Wallace, N D Walker

Related Concepts

Anaerobiosis
Bos indicus
Sulfite Cellulose
Digestion
DNA, Bacterial
Recombination Joint
Fermentation
Genetic Engineering
Episomes
Rumen

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Lipidomics & Rhinovirus Infection

Lipidomics can be used to examine the lipid species involved with pathogenic conditions, such as viral associated inflammation. Discovered the latest research on Lipidomics & Rhinovirus Infection.

Alzheimer's Disease: MS4A

Variants within the membrane-spanning 4-domains subfamily A (MS4A) gene cluster have recently been implicated in Alzheimer's disease in genome-wide association studies. Here is the latest research on Alzheimer's disease and MS4A.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Torsion Dystonia

Torsion dystonia is a movement disorder characterized by loss of control of voluntary movements appearing as sustained muscle contractions and/or abnormal postures. Here is the latest research.

Generating Insulin-Secreting Cells

Reprogramming cells or using induced pluripotent stem cells to generate insulin-secreting cells has significant therapeutic implications for diabetics. Here is the latest research on generation of insulin-secreting cells.

Central Pontine Myelinolysis

Central Pontine Myelinolysis is a neurologic disorder caused most frequently by rapid correction of hyponatremia and is characterized by demyelination that affects the central portion of the base of the pons. Here is the latest research on this disease.

Epigenome Editing

Epigenome editing is the directed modification of epigenetic marks on chromatin at specified loci. This tool has many applications in research as well as in the clinic. Find the latest research on epigenome editing here.