Prospects of chitosan-based scaffolds for growth factor release in tissue engineering

International Journal of Biological Macromolecules
P R Sivashankari, M Prabaharan

Abstract

Tissue engineering is concerned about the rejuvenation and restoration of diseased and damages tissues/organs using man-made scaffolds that mimic the native environment of the cells. In recent years, a variety of biocompatible and biodegradable natural materials is employed for the fabrication of such scaffolds. Of these natural materials, chitosan is the most preferred one as it imitates the extracellular matrix (ECM) of the cells. Moreover, chitosan-based materials are pro-angiogenic and have antibacterial activity. These materials can be easily fabricated into the desired shape of the scaffolds that are suitable for tissue support and regeneration. Growth factors are small proteins/peptides that support and enhance the growth and differentiation of cells into a specific lineage. It has been observed that scaffolds capable of delivering growth factor promote tissue repair and regeneration at a faster rate when compared to scaffolds without growth factor. The present review focuses on the recent developments on chitosan-based scaffolds for the delivery of growth factors thereby improving and enhancing tissue regeneration.

References

Dec 16, 2006·International Journal of Oral and Maxillofacial Surgery·X NieY Jin
Dec 23, 2008·Journal of Controlled Release : Official Journal of the Controlled Release Society·Xufeng NiuQixin Zheng
Mar 3, 2009·Journal of Controlled Release : Official Journal of the Controlled Release Society·Yufeng ZhangXiangrong Cheng
Sep 24, 2009·Tissue Engineering. Part a·Patrícia B MalafayaRui L Reis
Dec 8, 2009·Journal of Controlled Release : Official Journal of the Controlled Release Society·Beatriz De la RivaCarmen Evora
Aug 20, 2010·Journal of the Royal Society, Interface·Kangwon LeeDavid J Mooney
Jul 6, 2013·Materials Science & Engineering. C, Materials for Biological Applications·Samit K NandiDebabrata Basu
Apr 24, 2015·ACS Applied Materials & Interfaces·Yuanman YuChangsheng Liu
May 9, 2015·Methods : a Companion to Methods in Enzymology·Yun XiaoMilica Radisic
Sep 2, 2015·Journal of Controlled Release : Official Journal of the Controlled Release Society·Kunal J Rambhia, Peter X Ma

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Citations

Mar 31, 2016·Advanced Healthcare Materials·Qi GuJeremy M Crook
Apr 17, 2017·International Journal of Biological Macromolecules·Ijaz BanoMuhammad Younus
Dec 13, 2017·Science and Technology of Advanced Materials·Shu-Jyun CaiGou-Jen Wang
May 24, 2019·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Gregor KravanjaMaja Leitgeb
Apr 8, 2020·Handchirurgie, Mikrochirurgie, plastische Chirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft für Handchirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft für Mikrochirurgie der Peripheren Nerven und Gefässe : Organ der Vereinigung der Deut·Marie-Luise KlietzMatthias Aitzetmüller
Aug 11, 2018·Regenerative Biomaterials·Tinke-Marie De WitteNicholas A Peppas
Jan 27, 2019·Materials·Ivan Joseph Hall BarrientosPaul Coats
Aug 5, 2017·Materials·Udeni Gunathilake T M SampathPai-Chen Lin
Jan 5, 2019·Applied Microbiology and Biotechnology·Muhammad Shahid Riaz RajokaShahid Mahmood
Nov 9, 2019·Current Pharmaceutical Design·Tatiana Rita de Lima NascimentoLúcio Roberto Cançado Castellano
Mar 3, 2020·Biomedical Materials·Mahboubeh JafarkhaniMohammad Ali Shokrgozar
Feb 25, 2020·Journal of the Mechanical Behavior of Biomedical Materials·Fahad AlamS Kumar
Apr 4, 2021·Polymers·M Sai Bhargava ReddyKishor Kumar Sadasivuni
Jul 3, 2021·International Journal of Molecular Sciences·Chih-Hsin WangSheng-Der Hsu
Jul 3, 2021·Micromachines·David Angelats LoboJoaquim Ciurana
Dec 12, 2019··Hanaa Shuker MahmoodMohammed Kadhim Jawad

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