Prostacyclin and blood glucose levels in humans and rabbits

Prostaglandins
A Dembińska-KiećT Zelazny

Abstract

In patients with peripheral vascular disease and in healthy rabbits, infusion of PGI2 but not of 6-keto PGF1 alpha induced a rise in blood glucose level and a pathological deviation in glucose tolerance test. In experiments in vitro, the increased concentrations of glucose produced dose-dependent inhibition of PGI2 release from isolated rat aortic rings. The link between PGI2 and carbohydrate metabolism is discussed.

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Jul 1, 1995·Prostaglandins·A JawerbaumM A de Gimeno
Jun 1, 1983·Prostaglandins, Leukotrienes, and Medicine·A L GimenoM F Gimeno
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