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Prostacyclin reversal of lethal endotoxemia in dogs

The Journal of Clinical Investigation

Apr 1, 1981

M M KrauszH B Hechtman

PMID: 7009654

Abstract

Severe endotoxemia, a condition where microembolization and intravascular coagulation are thought to play important roles, was treated experimentally with prostacyclin (PGI(2)). In a study of 24 dogs, 8 control animals injected with 1.75 mg.kg(-1) of endotoxin died within 24 h. Six anim...read more

Mentioned in this Paper

Arterial Pulse Pressure
Endotoxemia
Lung
Flow of Urine
Depressed - Symptom
White Blood Cell Count Procedure
Flolan
Differential White Blood Cell Count Procedure
Fibrin-fibrinogen Split Products Assay
Leukocytes
Paper Details
References
  • References13
  • Citations38
12
  • References13
  • Citations38
1234

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Prostacyclin reversal of lethal endotoxemia in dogs

The Journal of Clinical Investigation

Apr 1, 1981

M M KrauszH B Hechtman

PMID: 7009654

DOI:

Abstract

Severe endotoxemia, a condition where microembolization and intravascular coagulation are thought to play important roles, was treated experimentally with prostacyclin (PGI(2)). In a study of 24 dogs, 8 control animals injected with 1.75 mg.kg(-1) of endotoxin died within 24 h. Six anim...read more

Mentioned in this Paper

Arterial Pulse Pressure
Endotoxemia
Lung
Flow of Urine
Depressed - Symptom
White Blood Cell Count Procedure
Flolan
Differential White Blood Cell Count Procedure
Fibrin-fibrinogen Split Products Assay
Leukocytes

Feeds With Similar Papers

Blood Clotting Disorders

Thrombophilia includes conditions with increased tendency for excessive blood clotting. Blood clotting occurs when the body has insufficient amounts of specialized proteins that make blood clot and stop bleeding. Here is the latest research on blood clotting disorders.

Dopamine & Behavior

Dopamine is a neurotransmitter and a hormone commonly associated with the brain's pleasure and reward system. Here is the latest research on its role in affecting and guiding human behaviour.

Paper Details
References
  • References13
  • Citations38
12
  • References13
  • Citations38
1234

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