PMID: 9167212Apr 1, 1997Paper

Prostaglandin E and F2 alpha concentration in the cervical mucus and mechanism of cervical ripening

Prostaglandins
J J Platz-ChristensenN Wiqvist

Abstract

To study the mechanism of cervical ripening by determination of prostaglandin E (PGE) and F2 alpha (PGF2 alpha) concentrations in cervical mucus during the course of pregnancy. Cervical mucus was collected from 99 pregnant women attending the mother care unit of the department. Women with sexual intercourse within the last 24 hours before sampling and subjects with bacterial vaginosis were analysed separately. Eleven women had sexual intercourse within 24 hours before sampling. The concentration of PGE in their cervical mucus was high corresponding to 2000-4000 pg/mg w w lasting for a period of 10-12 hours postcoitally, whereas the levels of PGF 2 alpha only increased slightly. Bacterial vaginosis was accomplished by a slight but significant elevation of PGF2 alpha levels but only of a minor increment of the PGE values. The prostaglandin concentrations in the mucus from the remaining 68 women were for PGE 102.75 +/- 111.51 and for PGF2 alpha 97.54 +/- 82.48 pg/mg w w (mean +/- SD). Although the values were scattered the concentrations remained at approximately the same level throughout pregnancy and there was no tendency towards an increment during the last weeks of pregnancy when cervical maturation is apparent. Cervical softe...Continue Reading

References

Jan 1, 1978·Acta Obstetricia Et Gynecologica Scandinavica·L WingerupU Ulmsten
Apr 1, 1989·American Journal of Perinatology·M TothA R Fuchs
Sep 1, 1986·Prostaglandins, Leukotrienes, and Medicine·R W KellyR F Seamark
Apr 1, 1987·International Journal of Andrology·E BendvoldP Eneroth
Jan 1, 1974·The Journal of Obstetrics and Gynaecology of the British Commonwealth·A A CalderK Hillier
Jan 1, 1983·British Journal of Hospital Medicine·S G Dawson, J R Harris
Nov 1, 1993·American Journal of Obstetrics and Gynecology·T Kurki, O Ylikorkala
Nov 1, 1993·American Journal of Obstetrics and Gynecology·J J Platz-ChristensenN Wiqvist
Sep 1, 1993·American Journal of Obstetrics and Gynecology·C G BarclayA A Calder

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Citations

Dec 20, 2003·Prostaglandins, Leukotrienes, and Essential Fatty Acids·Frank Hertelendy, Tamás Zakár
Jan 15, 1999·Prostaglandins, Leukotrienes, and Essential Fatty Acids·E GonzálezM Gimeno
Oct 2, 2003·Prostaglandins & Other Lipid Mediators·K J Sales, H N Jabbour
Dec 4, 2009·Prostaglandins, Leukotrienes, and Essential Fatty Acids·J H DurnA Nicolaou
Feb 24, 2006·The Veterinary Journal·C W WeemsR D Randel
Feb 14, 2006·Placenta·A BeauséjourM Brochu
Nov 30, 2002·The Journal of Family Planning and Reproductive Health Care·C M Pyper, J Knight
Jul 30, 2017·Scientific Reports·Christine M O'BrienAnita Mahadevan-Jansen
Oct 13, 2021·American Journal of Obstetrics & Gynecology MFM·Liran HierschNir Melamed

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