PMID: 6106578May 1, 1980Paper

Prostaglandin F production by tissue explants from term pregnancies

International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics
R LackritzD Tulchinsky

Abstract

Explants of various tissues obtained from pregnant women at term and from nonpregnant women were maintained in culture and their capacities to synthesize prostaglandin (PGF) were evaluated. Myometrial and decidual tissues from pregnant women produced significantly smaller amounts of PGF than those from nonpregnant women, suggesting that PGF production is inhibited during gestation. Decidual PGF synthesis was also inhibited by the addition of progesterone, estradiol or indomethacin. The PGF synthesis of the chorion of women in labor was lower than that of women not in labor. In the later group, the cohrion, decidua and myometrium produced significant amounts of PGF, but amniotic PGF production was negligible. Our findings show that the decidua and chorion, as well as the myometrium, are potentially important sources of PGF production. PGF synthesis during pregnancy also may be affected by local inhibitory influences.

References

Jan 1, 1978·Prostaglandins·M J DuchesneA C de Paulet
Nov 1, 1977·Prostaglandins·K I Williams, I Downing
Feb 1, 1978·Prostaglandins·M D MitchellA C Turnbull
Sep 1, 1976·American Journal of Obstetrics and Gynecology·F Dray, R Frydman
Feb 1, 1976·British Journal of Obstetrics and Gynaecology·M J Keirse, A C Turnbull
Feb 1, 1975·Prostaglandins·E M Cane, C A Villee
Nov 1, 1975·British Journal of Obstetrics and Gynaecology·M J Keirse, A C Turnbull
Aug 27, 1971·Nature·G C Liggins, S Grieves
Apr 1, 1967·The Journal of Obstetrics and Gynaecology of the British Commonwealth·S M Karim, J Devlin

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

The Journal of Clinical Endocrinology and Metabolism
B F MitchellJ R Challis
International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics
R E GarfieldM J Harper
© 2021 Meta ULC. All rights reserved