PMID: 2116333Sep 1, 1990Paper

Prostaglandins: PGF2 alpha, PGE2, 6-keto-PGF1 alpha and TXB2 serum levels in dysmenorrheic adolescents before, during and after treatment with oral contraceptives

European Journal of Obstetrics, Gynecology, and Reproductive Biology
G CreatsasD Aravantinos

Abstract

Ten adolescents with primary dysmenorrhea (PD) were treated with the oral contraceptive (OC) Lyndiol 2.5 mg (R) for one cycle. The levels of PGF2 alpha, PGE2 and the metabolites of PGI2 and TXA2: 6-keto-PGF1 alpha and TXB2 were tested by a radioimmunoassay method during the 1st and 23rd day of the pre-treatment cycle (PrTC), the 23rd day of treatment (TC) and the 1st day of the post-treatment cycle (PoTC). The ratios PGF2 alpha/PGE2 and TXB2/6-keto-PGF1 alpha were also tested and compared during the above-mentioned days. Analytical comparison was made, for each Prostaglandin (PG) separately, between the 1st day of the PrTC and PoTC as well as the 23rd day of the PrTC and TC, respectively. All PG levels during TC and PoTC were found significantly lower, compared to those of the PrTC respectively. With regard to the ratios mentioned above, no statistically significant differences were found on the same days and cycles as previously stated. The reduction of the PG levels in PD patients after treatment with oral contraceptives, together with an improvement of the clinical findings of the disease, support the theory that oral contraceptives can be used for the treatment of PD cases, especially for those adolescents who also desire a...Continue Reading

References

Jan 1, 1983·Acta Obstetricia Et Gynecologica Scandinavica. Supplement·N WiqvistL Wilhelmsson
Nov 30, 1957·Nature·V R PICKLES

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Citations

Dec 12, 2012·Archives of Gynecology and Obstetrics·Maryam Sanjary PourAzra Rabbani Chadegani
Jul 1, 1997·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·G Creatsas
May 19, 2001·Journal of Pediatric and Adolescent Gynecology·A R Davis, C L Westhoff
Nov 29, 2014·Evidence-based Complementary and Alternative Medicine : ECAM·Kyoung-Sun ParkChang-Hoon Lee
Dec 6, 2002·Journal of Obstetric, Gynecologic, and Neonatal Nursing : JOGNN·Beth A Collins SharpM Yusoff Dawood
Mar 12, 2004·Expert Opinion on Pharmacotherapy·Guillermo Di GirolamoClaudio D González
Jan 25, 2006·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·Chi-Mou JuangChih-Yao Chen
Sep 30, 2016·Pharmacological Reviews·Birgit M DietzJudy L Bolton
Apr 22, 2008·The Cochrane Database of Systematic Reviews·X ZhuC A Smith
Dec 6, 2017·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·I VianM Markoski
Aug 2, 2006·Obstetrics and Gynecology·M Yusoff Dawood
Jun 25, 2008·Annals of the New York Academy of Sciences·Zeev Harel
Sep 21, 2019·Obstetrics & Gynecology Science·Jee Young JeongByung Seok Lee
May 20, 2000·Annals of the New York Academy of Sciences·E Deligeoroglou
Nov 15, 2002·Paediatric Drugs·Zeev Harel

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