Prostanoid production by rat aortic endothelial cells by bradykinin and histamine

European Journal of Pharmacology
O F Cole, G P Lewis

Abstract

The present studies demonstrate that rat aortic endothelial cells, when stimulated with either bradykinin or histamine, caused the release of both PGI2 and PGE2. The method has also been used to characterize the histamine receptor involved which is H1-subtype. The findings suggest that prostanoid production by bradykinin and histamine constitutes an alternative mechanism to endothelium-derived relaxing factor in mediating vasodilatation.

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Citations

Oct 8, 2003·Toxicon : Official Journal of the International Society on Toxinology·Ana M BarbosaJosé C Cogo
Oct 24, 1998·Experimental Gerontology·M NakajimaK Yamanouchi
Jul 29, 2008·World Journal of Surgical Oncology·Margaret I Liang, William E Carson
Jan 1, 1992·Archives Internationales De Physiologie, De Biochimie Et De Biophysique·M K KrstićS K Krstić
Jun 26, 2002·Human Fertility : Journal of the British Fertility Society·Sandra J DowningHenry J Leese

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