PMID: 9422569Jan 9, 1998Paper

Prostate brachytherapy in patients with inflammatory bowel disease

International Journal of Radiation Oncology, Biology, Physics
A Grann, K E Wallner

Abstract

There are minimal data to support the perceived contraindication of radiation therapy in patients with inflammatory bowel disease (IBD). Because of widespread concern about the possibility of radiation-related morbidity in IBD patients, the posttreatment course for 6 patients with a history of IBD who were treated with 125I prostate implantation for early stage prostate cancer are reported here. Six patients with a prior history of IBD and Stage T1c-T2c prostatic carcinoma underwent 125I prostate brachytherapy from 1991-1996. Three patients had Crohn's disease and three had ulcerative colitis. The treatment plans were designed to treat the preimplant prostatic margin, as defined on planning CT scan, to 150 Gy. No special effort was made to minimize the rectal surface dose. Detailed records were available for all patients, and all patients were interviewed for this report. Follow-up ranged from 1 to 6 years (median: 3.7 years). None of the 6 patients experienced unusual or significant gastrointestinal side effects following implantation. All 6 patients remain free of GI complications. The rectal surface area that received > 100 Gy was kept below 10 mm2 in all patients, in accordance with previously published guidelines. Based on...Continue Reading

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May 15, 1995·International Journal of Radiation Oncology, Biology, Physics·K WallnerL Harrison

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Citations

Aug 5, 2000·International Journal of Radiation Oncology, Biology, Physics·D Y Gelblum, L Potters
Sep 25, 2001·International Journal of Radiation Oncology, Biology, Physics·D Y SongT L DeWeese
Mar 8, 2000·International Journal of Radiation Oncology, Biology, Physics·C G WillettD K Podolsky
Jan 25, 2013·World Journal of Gastroenterology : WJG·Abobakr K ShadadLaurence J Egan
Nov 6, 2013·Hematology/oncology Clinics of North America·Richard Khor, Scott Williams
Aug 19, 2008·Urology·Richard WilliamsonRonald M Benoit
Aug 5, 2006·International Journal of Radiation Oncology, Biology, Physics·Christopher A PetersRichard G Stock
May 30, 2015·Clinical Oncology : a Journal of the Royal College of Radiologists·D Tromp, D R H Christie
Oct 21, 2005·Clinical Journal of Oncology Nursing·Debra ZeroskiGregory S Merrick
Nov 23, 2006·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Aileen B ChenCraig C Earle
Apr 11, 2003·The Journal of Urology·Gregory S MerrickWayne M Butler
Jun 8, 2012·Reviews in Medical Virology·Josef WagnerCarl D Kirkwood
Apr 19, 2002·The Oncologist·Brian H Chon, Jay S Loeffler
Nov 13, 2019·Digestive Diseases and Sciences·Jaehyun Kim, Linda A Feagins
Dec 15, 2016·Brachytherapy·Brian J DavisNeha Vapiwala

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