Prostate cancer detection with biparametric magnetic resonance imaging (bpMRI) by readers with different experience: performance and comparison with multiparametric (mpMRI)

Abdominal Radiology
Marco GattiPaolo Fonio

Abstract

To study the detection of clinically significant prostate cancer (PCa) by readers with different experience, comparing performance with biparametric magnetic resonance imaging (bmMRI) and with the reference multiparametric (mpMRI). Retrospective analysis of 68 patients with mpMRI of the prostate at 1.5 Tesla using a 32 phased-array coil. Forty-five patients (cases) underwent radical prostatectomy, whereas 23 (controls) had a negative prostate biopsy and ≥ 2.5 years of negative follow-up. Six observers (two with 1000 cases interpreted, two with 300, two with 100) performed the analysis first with bpMRI including diffusion-weighted imaging (DWI), apparent diffusion coefficient (ADC) maps and T2-weighted (T2W) imaging in three planes and, after 1 month, with mpMRI, adding dynamic contrast enhancement (DCE). The performance was quantified by sensitivity (SNS), specificity (SPC) and area under the curve (AUC) of the ROC (Receiver Operating Characteristics) procedure. Concordance within observers of equivalent experience was good (weighted Cohen's k ≈ 0.7). The two expert readers performed as well in bpMRI as in mpMRI (SNS = 0.91-0.96, AUC = 0.86-0.93; p ≥ 0.10); readers with 300 cases performed well in mpMRI, but significantly worse...Continue Reading

References

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Citations

Nov 26, 2019·Minerva gastroenterologica e dietologica·Marco GattiRiccardo Faletti
Mar 13, 2020·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·Mohammad SherafatiKevin M Koch
May 5, 2020·Journal of Magnetic Resonance Imaging : JMRI·Anwar R PadhaniGeert Villeirs
Oct 1, 2020·Journal of Investigative Surgery : the Official Journal of the Academy of Surgical Research·Yifei ChengGong Cheng
Oct 24, 2019·Current Opinion in Urology·Joseph M NorrisVeeru Kasivisvanathan
Mar 1, 2020·Nature Reviews. Clinical Oncology·Derek J Lomas, Hashim U Ahmed
Jun 13, 2020·World Journal of Urology·Paolo GonteroBadrinath Konety
May 10, 2020·Abdominal Radiology·Sirisin KamsutNelly Tan
Oct 10, 2019·Radiology·Anwar R Padhani, Baris Turkbey
Aug 9, 2019·European Radiology Experimental·Renato CuocoloMassimo Imbriaco
Sep 10, 2020·Postgraduate Medicine·William W French, Eric M Wallen
Jan 28, 2021·AJR. American Journal of Roentgenology·Renato CuocoloArnaldo Stanzione
Nov 3, 2020·Current Urology Reports·Neha Udayakumar, Kristin K Porter
May 1, 2021·Diagnostics·Rima HajjoAlexander Tropsha
Aug 10, 2021·Insights Into Imaging·Andreas M HötkerOlivio F Donati
Nov 27, 2021·The British Journal of Radiology·Alexander P ColeMark Emberton

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