Prostate cancer diagnosed after prostate-specific antigen testing of men without clinical signs of the disease: a population-based study from the National Prostate Cancer Register of Sweden

Scandinavian Journal of Urology and Nephrology
Ola BrattSteering Committee of the Swedish National Prostate Cancer Register

Abstract

To investigate the effects of prostate-specific antigen (PSA) testing of men without clinical signs of prostate cancer on the incidence of prostate cancer in Sweden. Information on the cause of diagnosis, tumour characteristics and primary treatment for patients diagnosed with prostate cancer between January 1999 and December 2007 was extracted from the National Prostate Cancer Register of Sweden. This register includes data for 95% of Swedish prostate cancer cases. The total age-standardized annual incidence of prostate cancer per 100,000 men increased from 187 in 1999 to 233 in 2004, but decreased thereafter to 196 in 2007. The incidence of asymptomatic cases also peaked in 2004 (at 62 per 100,000 men), but varied six-fold between different counties in that year (16-98 per 100,000 men). Asymptomatic cases (n = 17,143) constituted 15% of all new cases in 2000 and 30% in 2007. Almost as many cases were diagnosed in stage T1c in men with symptoms, usually from the lower urinary tract. Together these two groups constituted 29% of all new cases in 2000 and 52% in 2007. It was estimated that at least one-third of all Swedish men aged 50-75 years had a PSA test between 2000 and 2007. Even though screening for prostate cancer is not ...Continue Reading

References

Oct 8, 1987·The New England Journal of Medicine·T A StameyE Redwine
Nov 1, 2005·Scandinavian Journal of Urology and Nephrology·Pär StattinJan-Erik Johansson
Feb 9, 2007·Annals of Oncology : Official Journal of the European Society for Medical Oncology·J FerlayP Boyle
Oct 9, 2007·European Urology·Axel HeidenreichUNKNOWN European Association of Urology
Oct 16, 2007·Scandinavian Journal of Urology and Nephrology·Jan AdolfssonPär Stattin
Aug 6, 2008·Annals of Internal Medicine·Kenneth LinUNKNOWN U.S. Preventive Services Task Force
Sep 4, 2008·Acta Oncologica·Lotti BarlowMats Talbäck
Jan 22, 2009·BJU International·Roderick C N van den BerghFritz H Schröder
Mar 12, 2009·Journal of the National Cancer Institute·Gerrit DraismaHarry de Koning
Mar 20, 2009·The New England Journal of Medicine·Fritz H SchröderUNKNOWN ERSPC Investigators
May 29, 2009·CA: a Cancer Journal for Clinicians·Ahmedin JemalMichael J Thun
Jun 2, 2009·European Urology·Per-Anders AbrahamssonManfred Wirth
Aug 13, 2009·Journal of the National Cancer Institute·Gerd GigerenzerRonald Frank
Sep 2, 2009·Journal of the National Cancer Institute·H Gilbert Welch, Peter C Albertsen

❮ Previous
Next ❯

Citations

Jan 19, 2010·Proceedings of the National Academy of Sciences of the United States of America·Jianfeng XuWilliam B Isaacs
Jun 22, 2010·Journal of the National Cancer Institute·Pär StattinUNKNOWN National Prostate Cancer Register (NPCR) of Sweden
Sep 26, 2009·BMJ : British Medical Journal·Benny HolmströmPär Stattin
May 9, 2009·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Fredrik E WiklundJianfeng Xu
Aug 19, 2011·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Daniel W LinJanet L Stanford
Aug 29, 2012·Clinical Cancer Research : an Official Journal of the American Association for Cancer Research·Ruth EtzioniHans-Olov Adami
Oct 3, 2013·PloS One·Mieke Van HemelrijckJan Adolfsson
Dec 21, 2011·CMAJ : Canadian Medical Association Journal = Journal De L'Association Medicale Canadienne·Mattias Johansson, Pär Stattin
Nov 8, 2011·The British Journal of General Practice : the Journal of the Royal College of General Practitioners·Brian S BuckleyAziz Sheikh
Jan 14, 2011·The American Journal of Clinical Nutrition·Mara M EpsteinLorelei A Mucci
Dec 15, 2015·International Journal of Cancer. Journal International Du Cancer·Frederik B ThomsenPär Stattin
Jan 23, 2013·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·Sigrid CarlssonAnna Bill-Axelson
Dec 15, 2010·International Journal of Cancer. Journal International Du Cancer·Håkan JonssonPär Stattin
Oct 24, 2012·Cancer·Christel HäggströmPär Stattin
May 19, 2016·Scandinavian Journal of Urology·Anders BjartellOlof Akre
Nov 3, 2017·Scandinavian Journal of Urology·Kaire InnosKatrin Lang
Jan 20, 2020·BJU International·Ola BrattPär Stattin
May 22, 2021·Health Sociology Review : the Journal of the Health Section of the Australian Sociological Association·Jelmer Brüggemann

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

The New England Journal of Medicine
Fang FangUnnur Valdimarsdóttir
European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)
Freddie BrayAnssi Auvinen
European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)
Anna Bill-AxelsonGunnar Steineck
© 2021 Meta ULC. All rights reserved