Prostate Cancer Diagnosis on Repeat Magnetic Resonance Imaging-Transrectal Ultrasound Fusion Biopsy of Benign Lesions: Recommendations for Repeat Sampling.

The Journal of Urology
Raju ChelluriPeter Pinto

Abstract

Urologists face a dilemma when a lesion identified on multiparametric magnetic resonance imaging is benign on image guided fusion biopsy. We investigated the detection rate of prostate cancer on repeat fusion biopsy in multiparametric magnetic resonance imaging lesions initially found to be pathologically benign on fusion biopsy. We reviewed the records of all patients from 2007 to 2014 who underwent multiparametric magnetic resonance imaging and image guided fusion biopsy. We identified men who underwent rebiopsy of the same discrete lesion after initial fusion biopsy results were benign. Data were documented on a per lesion basis. We manually reviewed UroNav system (Invivo, Gainesville, Florida) needle tracking to verify accurate image registration. Multivariate analysis was used to identify clinical and imaging factors predictive of prostate cancer detection at repeat fusion biopsy. A total of 131 unique lesions were rebiopsied in 90 patients. Of these 131 resampled lesions 21 (16%) showed prostate cancer, which in 13 (61.9%) was Gleason 3 + 3. On multivariate analysis only lesion growth on repeat multiparametric magnetic resonance imaging was significantly associated with prostate cancer detection at repeat biopsy (HR 3.274...Continue Reading

References

Feb 24, 2010·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Peter H GannEdward Vonesh
Feb 11, 2014·Diagnostic and Interventional Radiology : Official Journal of the Turkish Society of Radiology·Cheng William HongPeter A Pinto
May 9, 2014·Diagnostic and Interventional Radiology : Official Journal of the Turkish Society of Radiology·Soroush Rais-BahramiPeter A Pinto
Aug 26, 2014·The Journal of Urology·Dima RaskolnikovPeter A Pinto
Sep 25, 2014·BioMed Research International·Arvin K GeorgeSoroush Rais-Bahrami
Jan 28, 2015·JAMA : the Journal of the American Medical Association·M Minhaj SiddiquiPeter A Pinto
Apr 8, 2015·The Journal of Urology·Scott E EggenerWilliam T Lowrance
May 29, 2015·Current Urology Reports·Michele FascelliPeter A Pinto
Jun 13, 2015·Current Urology Reports·Thomas P FryeArvin K George

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Citations

May 4, 2016·Abdominal Radiology·Arvin K GeorgePeter A Pinto
Jun 17, 2016·International Urology and Nephrology·Akhil MuthigiPeter A Pinto
Jul 22, 2017·The Journal of Urology·Edward ChangLeonard S Marks
Jul 3, 2018·Korean Journal of Radiology : Official Journal of the Korean Radiological Society·Wulphert VenderinkJurgen J Fütterer
Sep 7, 2019·Therapeutic Advances in Urology·Justin StreicherAbhinav Sidana

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