Prostate cancer epigenetics: a review on gene regulation.

Gene Regulation and Systems Biology
Lena DiawJohn W Gillespie

Abstract

Prostate cancer is the most common cancer in men in western countries, and its incidence is increasing steadily worldwide. Molecular changes including both genetic and epigenetic events underlying the development and progression of this disease are still not well understood. Epigenetic events are involved in gene regulation and occur through different mechanisms such as DNA methylation and histone modifications. Both DNA methylation and histone modifications affect gene regulation and play important roles either independently or by interaction in tumor initiation and progression. This review will discuss the genes associated with epigenetic alterations in prostate cancer progression: their regulation and importance as possible markers for the disease.

References

Oct 10, 1975·Science·A Ruiz-CarrilloV G Allfrey
Mar 1, 1992·Trends in Pharmacological Sciences·T SakuraiT Masaki
Nov 1, 1991·DNA and Cell Biology·C K GlassZ H Han
Mar 1, 1990·The New England Journal of Medicine·B R Zetter
Aug 1, 1988·The American Journal of Surgical Pathology·J E McNeal
Apr 1, 1989·Proceedings of the National Academy of Sciences of the United States of America·A InoueT Masaki
May 24, 1974·Science·R D Kornberg, J O Thomas
Jun 1, 1995·Current Opinion in Genetics & Development·S H Cross, A P Bird
May 25, 1995·The New England Journal of Medicine·M E TaplinS P Balk
Apr 1, 1995·Trends in Genetics : TIG·A Kamb
May 15, 1995·Genes & Development·C J Sherr, J M Roberts
Nov 22, 1994·Proceedings of the National Academy of Sciences of the United States of America·W H LeeW G Nelson
Feb 15, 1994·Proceedings of the National Academy of Sciences of the United States of America·K BerhaneB Mannervik
Oct 1, 1995·Journal of Molecular Medicine : Official Organ of the Gesellschaft Deutscher Naturforscher Und Ärzte·J R Biggs, A S Kraft
Apr 30, 1996·Annals of the New York Academy of Sciences·G CarrubaL A Castagnetta
Nov 1, 1996·American Journal of Clinical Pathology·M NagabhushanM S Sy
Dec 1, 1996·Japanese Journal of Pharmacology·K GotoY Kasuya
Jan 1, 1997·Current Opinion in Oncology·M S SyD Liu
Jan 1, 1997·Advances in Cancer Research·D NaorD Ish-Shalom
Apr 1, 1997·Molecular Pathology : MP·Z Rudzki, S Jothy
Jan 27, 1998·Pharmacological Research : the Official Journal of the Italian Pharmacological Society·A Ortega Mateo, A A de Artiñano
Apr 16, 1998·Genes & Development·K Struhl
Jul 11, 1998·Molecular Cell·H HermekingB Vogelstein
Jul 29, 1998·Chemico-biological Interactions·C J HendersonC R Wolf
Nov 21, 1998·Biochimica Et Biophysica Acta·M Ruas, G Peters
Feb 6, 1999·International Journal of Cancer. Journal International Du Cancer·N S VerkaikG J Van Steenbrugge
Aug 24, 1999·Cancer Metastasis Reviews·P S Rennie, C C Nelson
Dec 14, 1999·The American Journal of Pathology·A M De MarzoW G Nelson

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