PMID: 16519827Mar 8, 2006Paper

Prostate cancer pathologic stage pT2b (2002 TNM staging system): does it exist?

International Braz J Urol : Official Journal of the Brazilian Society of Urology
Maisa M QuintalAthanase Billis

Abstract

In the 1997 TNM staging system, tumors were classified into a single subdivision: T2a, and bilateral tumor involvement (T2b). In the 2002 TNM staging system, tumors are subclassified as T2a (less than one half of one lobe involvement), T2b (more than one half of one lobe involvement), and T2c (bilateral involvement). A recent study questioned the existence of a true pathologic pT2b tumor. The aim of our study is to verify this question. The study population consisted of 224 men submitted to radical retropubic prostatectomy. The surgical specimens were histologically evaluated by complete embedding and whole-mount processing. Tumor extent was evaluated by a point-count method. The surgical specimens were staged according to the 2002 TNM staging system. Using the 2002 TNM criteria, the surgical specimens were classified as pT2a, 28 (12.50%); pT2b, 0 (0%); pT2c, 138 (61.61%); pT3a, 30 (13.39%); and, pT3b, 28 (12.50%). Using the point-count method for tumor extent evaluation, the minimum and maximum total points obtained in unilateral tumors were 192 and 368 points, respectively; the most extensive unilateral tumor showed 68 positive points (less than half the minimum total point-count). Using the point-count method for tumor exten...Continue Reading

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Citations

Aug 16, 2008·World Journal of Urology·Hashim Uddin Ahmed, Mark Emberton
Feb 22, 2011·International Urology and Nephrology·Athanase BillisUbirajara Ferreira
Sep 8, 2010·Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc·Theo H van der KwastUNKNOWN ISUP Prostate Cancer Group
Oct 30, 2007·Nature Clinical Practice. Oncology·Hashim Uddin AhmedMark Emberton
Aug 12, 2009·Southern Medical Journal·Robert A Nathan
Jul 7, 2012·Southern Medical Journal·Caitlin Lee ShamroeSharon B Weissman
Dec 23, 2011·Journal of Geriatric Physical Therapy·Eric G Johnson, Jonathan D Meltzer
Apr 13, 2007·Drugs·Anjuli Nayak, Ronald B Langdon
Mar 19, 2014·Pathology, Research and Practice·Paulo Roberto Fontes AthanazioDaniel Abensur Athanazio
Oct 16, 2012·Seminars in Diagnostic Pathology·Adeboye O Osunkoya, David J Grignon
Sep 18, 2009·The Journal of Urology·Yakup KordanDaniel A Barocas
Aug 2, 2008·BJU International·Sung Kyu HongSang Eun Lee
Jan 19, 2007·American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics·Dina RuanoJoana Almeida Palha
Aug 8, 2007·Journal of Biomedical Materials Research. Part B, Applied Biomaterials·Regina AmaralMarco Antonio Bottino
Nov 6, 2007·International Braz J Urol : Official Journal of the Brazilian Society of Urology·Jose C AlmeidaFlorencio Figueiredo
Jul 27, 2006·Internal Medicine Journal·A Y Peleg, D L Paterson
Dec 20, 2007·American Journal of Clinical Pathology·Jonathan I EpsteinUNKNOWN Association of Directors of Anatomic and Surgical Pathology
Jan 17, 2019·International Braz J Urol : Official Journal of the Brazilian Society of Urology·Athanase BillisUbirajara Ferreira

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