Prostate cancer-related anxiety in long-term survivors after radical prostatectomy

Journal of Cancer Survivorship : Research and Practice
Valentin H MeissnerAndreas Dinkel

Abstract

Knowledge of the psychological distress of long- and very long-term (>10 years) prostate cancer (PC) survivors is limited. This study intended to examine the parameters influencing anxiety related to prostate-specific antigen (PSA) and PC in long-term survivors after radical prostatectomy. We surveyed 4719 PC survivors from the German multicenter prospective database "Familial Prostate Cancer." We evaluated the association of PC-related anxiety (MAX-PC) with sociodemographic characteristics, family history of PC, global health status/quality of life (EORTC QLQ-C30), depression and anxiety (PHQ-2; GAD-2), latest PSA level, time since radical prostatectomy, and current therapy. The survey participants' mean age was 75.2 years (SD = 6.5). Median follow-up was 11.5 years, and 19.5% of participants had survived more than 15 years since the initial treatment. The final regression analysis found that younger age, lower global health status/quality of life, higher depression and anxiety scores, higher latest PSA level, and shorter time since radical prostatectomy predicted increased PSA-related anxiety and PC anxiety. Familial PC was predictive only of PSA anxiety (all p < 0.05). The final model explained 12% of the variance for PSA an...Continue Reading

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Citations

Sep 2, 2019·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Marius HaackMarie-Luise Dierks
Apr 2, 2020·Prostate Cancer·Ernesto Sánchez SánchezJesús Castiñeiras Fernández
Mar 25, 2019·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Amy Y ZhangHui Zhu
Jan 16, 2021·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Irène LassmannKathleen Herkommer
Jan 26, 2021·Current Urology·Konstantina G YiannopoulouIoannis P Anastasiou
Nov 18, 2020·Journal of Pain and Symptom Management·Mi-Chun ChouYing-Hsu Chang
Oct 9, 2019·Aktuelle Urologie·Veronika Elisabeth GoetheKathleen Herkommer
Apr 27, 2021·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Barbara M WollersheimAnnelies H Boekhout

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