Prostate movement during simulation resulting from retrograde urethrogram compared with "natural" prostate movement

International Journal of Radiation Oncology, Biology, Physics
Yu-Ming LiuMack Roach

Abstract

Retrograde urethrography (UG) is commonly used at the time of simulation to assist in defining the prostate apex. Some investigators have reported that performing the UG introduces error by causing prostate displacement. We investigate the movement of the prostate caused by the retrograde UG. Twenty-four patients treated with three-dimensional conformal radiotherapy for prostate cancer who had gold marker seeds placed into their prostates were studied. Marker seed locations at the time of simulation and on the portal images acquired just before the treatment were compared with the locations on digitally reconstructed radiographs (DRR). Movement in the superior-inferior and anteroposterior directions as seen on lateral images was measured from 402 portal images by offline customized imaging software and evaluated using analysis of variance methods for continuous variables and chi-square statistics for categoric variables. "Natural" nonrandom movement of the prostate around an "origin" as defined by markers on DRR was observed. This movement tends to be in a superior and anterior direction, with the average shift being 1 mm and 0.82 mm, respectively. The magnitude of movement in the superior direction averaged 2.88 mm compared wi...Continue Reading

References

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Citations

Nov 29, 2008·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Oscar MatzingerUNKNOWN EORTC Radiation Oncology Group
Jan 1, 2008·International Journal of Radiation Oncology, Biology, Physics·Melisa BoersmaTony Eng
Aug 13, 2005·Cancer radiothérapie : journal de la Société française de radiothérapie oncologique·P MaingonA Ammor
Feb 24, 2018·Medical Physics·Dale W LitzenbergDaniel E Spratt
Jul 11, 2019·Molecular and Clinical Oncology·Milly BuwengeAlessio G Morganti

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