Abstract
To characterize the disease progression and median survival of patients with prostate cancer (PCa) according to the prostatic-specific acid phosphatase (PAP) analysis in a population-based study from the Surveillance, Epidemiology, and End Results (SEER) database. Prostate cancer patients with completed PAP results were identified using the SEER database of the National Cancer Institute. The Mann-Whitney Sum test was utilized to compare the statistical significance for measurement data and ranked data. Data were stratified by ages, races, TNM Classification of Malignant Tumors (TNM), pathological grades, number of tumors, PAP, and survival duration. Multivariable logistic analysis was performed to identify predictors of the presence of invasion and metastases. Cox regression was analyzed for the factors associated with all-cause mortality and prostate cancer-specific mortality. Moreover, survival curve was used to detect the survival months. The unknown data were excluded from these tests. In total, there are 5184 PAP+ patients and 3161 PAP- patients involved. The Mann-Whitney Sum test showed that slightly greater tumor size (P = 0.03), elevated lymphatic (P = 0.005) and distant (P < 0.001) metastasis rate, higher pathological ...Continue Reading
References
Aug 1, 1976·Urology·D E JohnsonR P Gibbons
Dec 1, 1986·The Journal of Urology·D A GoldfarbR O Petersen
Mar 1, 1973·Cancer·A E ReifC M Robinson
Jan 1, 1984·The Journal of Urology·J A WhiteselR R Pfister
Oct 21, 1993·International Journal of Cancer. Journal International Du Cancer·L HakalahtiR Vihko
Apr 16, 1998·The Journal of Biological Chemistry·M F LinF F Lin
Jul 1, 1938·The Journal of Clinical Investigation·A B Gutman, E B Gutman
Jul 20, 2007·Cancer Research·Ileana B QuinteroPirkko T Vihko
Feb 5, 2008·Urology·L Christine FangKent Wallner
Mar 21, 2009·Virchows Archiv : an International Journal of Pathology·Sven GuniaAndreas Erbersdobler
Nov 16, 2011·Annals of the New York Academy of Sciences·Alexander KirschenbaumAlice C Levine
Feb 14, 2012·Current Opinion in Urology·Charles G Drake, Emmanuel S Antonarakis
Aug 29, 2012·Annals of Oncology : Official Journal of the European Society for Medical Oncology·W R Gerritsen
Sep 7, 2013·Biomolecules & Therapeutics·Hoon Young Kong, Jonghoe Byun
Nov 19, 2013·Clinical & Experimental Metastasis·Sandy R LarsonColm Morrissey
Feb 6, 2015·CA: a Cancer Journal for Clinicians·Lindsey A TorreAhmedin Jemal
May 12, 2015·The Journal of Urology·David F Penson
Oct 27, 2016·Endocrinology·Alexander KirschenbaumAlice C Levine
Feb 9, 2017·Prostate Cancer·Shahana SarwarMohammed Ishaq
Citations
Oct 2, 2020·Analytical and Bioanalytical Chemistry·Bo-Wen LiuFang-Ying Wu
Dec 12, 2020·Journal of Cellular Physiology·Giovana Rampazzo TeixeiraFrancisco Eduardo Martinez
Jan 19, 2021·Annals of Diagnostic Pathology·Stefania BergaminiElisa Bellei
Mar 7, 2021·International Journal of Molecular Sciences·Celina Terán-RamírezMarco A Ramos-Ibarra
Apr 4, 2021·Cancers·Erin G ShackletonStephanie E McArdle
Jun 15, 2021·Current Oncology Reports·Karie D Runcie, Matthew C Dallos
Dec 23, 2019·Pathobiology : Journal of Immunopathology, Molecular and Cellular Biology·Nami TakadaTsutomu Daa
Nov 12, 2021·The Prostate·Anne M A TryggestadGunnar Kvalheim