Prostatic conformal brachytherapy: 125I/103Pd postoperative dosimetric analysis

Radiation Oncology Investigations
G S MerrickH L Walbert

Abstract

Widespread replication of the favorable long-term results of prostatic conformal brachytherapy achieved by the Seattle group requires evidence that the technical quality of their implants is achievable elsewhere. Preplanning with a modified uniform loading algorithm using low activity seeds produces virtually no regions within the planning volume at less than the prescribed dose and no interconnected volumes between seeds at double the dose. The operative procedure stabilizes the prostate and locates the prostate targets, needles, and seeds and their relationship to the bladder and rectum using transverse and longitudinal ultrasound as well as contrast enhanced fluoroscopy. A detailed postoperative dosimetric analysis of patients with clinical T1/T2 adenocarcinoma of the prostate gland who underwent transperineal ultrasound conformal prostatic brachytherapy from March through June 1996 was performed. The analysis involved 7 consecutive patients implanted with 125I seeds and 5 consecutive patients implanted with 103Pd seeds. Median coverage to the full minimal peripheral dose (mPD) was 96% (range 80-99%) of the prostate volume. At 80% of the mPD, median isodose coverage was 100% (range 91-100%) of the prostate volume. Regarding ...Continue Reading

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Citations

Dec 21, 2000·International Journal of Radiation Oncology, Biology, Physics·D C BeyerF Puente
Mar 2, 2002·International Journal of Radiation Oncology, Biology, Physics·Juanita CrookMelania Pintilie
Apr 7, 1999·International Journal of Radiation Oncology, Biology, Physics·G S MerrickH J Blatt
May 29, 1999·International Journal of Radiation Oncology, Biology, Physics·G S MerrickJ H Lief
Jul 27, 1999·International Journal of Radiation Oncology, Biology, Physics·G S MerrickJ H Lief
Feb 3, 2000·International Journal of Radiation Oncology, Biology, Physics·G S MerrickM L Benson
Apr 12, 2000·International Journal of Radiation Oncology, Biology, Physics·G S MerrickA T Dorsey
Jan 11, 2001·Medical Dosimetry : Official Journal of the American Association of Medical Dosimetrists·G S MerrickJ T Dorsey
Mar 4, 2008·International Journal of Radiation Oncology, Biology, Physics·Judit Boda-HeggemannFrederik Wenz
Mar 7, 2006·The Journal of Urology·Gregory S MerrickEdward Adamovich
Mar 16, 2000·Medical Physics·W M ButlerA T Dorsey
Jun 9, 1999·Medical Physics·N YueF M Waterman

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