Prosthetic endocarditis treated by repeated heart transplantation: report of a successful case

Transplantation Proceedings
H-H HuangJ Wei

Abstract

The treatment of recurrent prosthetic valve endocarditis is extremely difficult. Heart transplantation (HT) may save the patient's life. Recurrent endocarditis, however, can occur after HT. This report described a patient who had under gone four conventional valve surgeries and three HTs successfully. In May 2000, a 14-year-old boy suffered from endocarditis with severe aortic valve regurgitation. He underwent aortic valve replacement (AVR) at another hospital. Due to prosthetic valve endocarditis, he displayed a severe paravalvular leakage and was transferred to our hospital where he underwent Bentall's operation in October 2000. Despite a full antibiotic course, he experienced a relapse of the prosthetic endocarditis with significant deterioration of the heart function and a progressively more severe paravalvular leak. Considering the difficulties of repair and the poor heart function, he underwent an HT in June 2003 and recovered well. Unfortunately, endocarditis with aortic valve regurgitation attacked him again after 3 years. Remarkably, all blood cultures were negative. A second AVR was performed in October 2006 with a Second Bentall's procedure 1 year later in 2007. In November 2009, the patient suddenly displayed cardio...Continue Reading

References

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Feb 11, 2011·Current Infectious Disease Reports·Larry M BushMaria T Perez

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Citations

Jan 30, 2015·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·Marie AymamiErwan Flécher
Oct 4, 2018·Transplant Infectious Disease : an Official Journal of the Transplantation Society·Katie M Murphy, Holenarasipur R Vikram
Jan 25, 2020·Transplant Infectious Disease : an Official Journal of the Transplantation Society·Filippo GivoneMatteo Bassetti

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