PMID: 1245960Mar 1, 1976Paper

Protamine sulfate titration for heparin activity in neonates with indwelling umbilical catheters

The Journal of Pediatrics
R T HallW J Braun


A rapid, simple, semimicro method for neutralization of heparin effect by titration with protamine sulfate is described. Protamine sulfate can be effectively employed to eliminate the effect of heparin on the APTT. Determination of true abnormalities of coagulation has important prognostic and therapeutic implications for the sick newborn infant.


Mar 18, 1974·JAMA : the Journal of the American Medical Association·E E Czapek
Jul 1, 1971·The Journal of Pediatrics·G B Merenstein
Jul 1, 1971·British Journal of Haematology·C FunkP W Straub


Jan 1, 1978·The Journal of Pediatrics·R L SchreinerC McNulty
May 1, 1980·Thrombosis Research·I Fabian, M Aronson

Related Concepts

Blood Coagulation Disorders
Blood Coagulation Tests
Neonatal Disorder
Protamine Sulfate (USP)
Structure of Umbilical Artery

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