PMID: 7030634Jan 1, 1981Paper

Protease activities in human tears

Current Eye Research
P K Tsung, F J Holly

Abstract

Several protease activities were measured in human tears by six specific substrates. The specific activity of cathepsin B-like enzyme was 7-fold higher in Orientals than in Caucasians. The trypsin-like and cathepsin C-like enzyme activities also showed 3 to 4-fold higher in Orientals than in Caucasians. However, the deviation in the activities of these two enzymes was high in both Orientals and Caucasians. Similar results were obtained when comparing the protease activities of tear collected by glass capillary and a filter-paper strip method. Since a surface-active small molecular weight fraction can be produced by incubation of freshly collected tears for 4 hours at 37 degrees C, the low molecular weight surfactant may be a proteolytic product.

References

Nov 1, 1979·Experimental Eye Research·A M GachonB Dastugue
Aug 18, 1975·Clinica Chimica Acta; International Journal of Clinical Chemistry·D L JohnsonR J Desnick
Jan 2, 1978·Clinica Chimica Acta; International Journal of Clinical Chemistry·N C Kar, C M Pearson
Nov 1, 1976·Proceedings of the National Academy of Sciences of the United States of America·H Neurath, K A Walsh
Jan 1, 1976·The British Journal of Ophthalmology·I A Mackie, D V Seal
Apr 1, 1973·The Biochemical Journal·A J Barrett
Jul 1, 1969·Archives of Ophthalmology·O P van Bijsterveld
May 1, 1972·Analytical Biochemistry·A J Barrett
Nov 15, 1973·The New England Journal of Medicine·P J CarmodyR G Davidson
Sep 1, 1980·American Journal of Ophthalmology·C MacKayM Pesche

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Citations

Jan 1, 1986·Journal of Ocular Pharmacology·W L Davis, J A Anderson
Feb 1, 1990·Experimental Eye Research·G B van SettenA Vaheri
May 19, 2001·European Journal of Biochemistry·H Goubran BotrosB David
Dec 3, 2003·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·F J OllivierG B Van Setten
Jul 5, 2008·Current Eye Research·Martin W LaFranceRoderick J Fullard
Aug 1, 1997·Current Eye Research·M SakataA R Beaton
Sep 1, 1985·Current Eye Research·R E Stratford, V H Lee

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