Protecting cows in small holder farms in East Africa from tsetse flies by mimicking the odor profile of a non-host bovid

PLoS Neglected Tropical Diseases
Rajinder K SainiChristian W Borgemeister

Abstract

For the first time, differential attraction of pathogen vectors to vertebrate animals is investigated for novel repellents which when applied to preferred host animals turn them into non-hosts thereby providing a new paradigm for innovative vector control. For effectively controlling tsetse flies (Glossina spp.), vectors of African trypanosomosis, causing nagana, repellents more powerful than plant derived, from a non-host animal the waterbuck, Kobus ellipsiprymnus defassa, have recently been identified. Here we investigate these repellents in the field to protect cattle from nagana by making cattle as unattractive as the buck. To dispense the waterbuck repellents comprising guaiacol, geranylacetone, pentanoic acid and δ-octalactone, (patent application) we developed an innovative collar-mounted release system for individual cattle. We tested protecting cattle, under natural tsetse challenge, from tsetse transmitted nagana in a large field trial comprising 1,100 cattle with repellent collars in Kenya for 24 months. The collars provided substantial protection to livestock from trypanosome infection by reducing disease levels >80%. Protected cattle were healthier, showed significantly reduced disease levels, higher packed cell vo...Continue Reading

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Citations

Jun 11, 2019·PLoS Neglected Tropical Diseases·Olabimpe Y OlaideBaldwyn Torto
Apr 21, 2020·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Ashish Radadiya, John A Pickett
Oct 10, 2018·Experimental & Applied Acarology·Margaret W KariukiMargaret M Ng'ang'a
Jun 26, 2020·Frontiers in Cellular Neuroscience·Souleymane DialloMerid N Getahun
Nov 1, 2020·Animals : an Open Access Journal From MDPI·Jacqueline Poldy

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