PMID: 7007851Jan 1, 1980Paper

Protection of mice against group B Streptococcus type Ia by IgG components of a rabbit antiserum

Medical Microbiology and Immunology
P H Cleat, C R Coid

Abstract

IgG fractions were separated by ion exchange chromatography on DEAE-cellulose from hyperimmune rabbit sera prepared against a group B streptococcus type Ia mouse-virulent strain. 50 microgram IgG in conjunction with ampicillin (200 mg/kg) protected mice more effectively against a lethal challenge than ampicillin (400 mg/kg) alone or ampicillin (200 mg/kg) combined with gentamicin (10 mg/kg), when administered up to 12 h after infection.

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