PMID: 9632624Jun 25, 1998Paper

Protection of mice against Plasmodium yoelii sporozoite challenge with P. yoelii merozoite surface protein 1 DNA vaccines

Infection and Immunity
S I BeckerM J Gardner

Abstract

Immunization of mice with DNA vaccines encoding the full-length form and C and N termini of Plasmodium yoelii merozoite surface protein 1 provided partial protection against sporozoite challenge and resulted in boosting of antibody titers after challenge. In C57BL/6 mice, two DNA vaccines provided protection comparable to that of recombinant protein consisting of the C terminus in Freund's adjuvant.

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Citations

Apr 20, 2001·Proceedings of the National Academy of Sciences of the United States of America·D C MayerL H Miller
Feb 26, 2004·Proceedings of the National Academy of Sciences of the United States of America·D C Ghislaine MayerLouis H Miller
Mar 13, 2009·Proceedings of the National Academy of Sciences of the United States of America·D C Ghislaine MayerLouis H Miller
Aug 26, 1999·Vaccine·C I de OliveiraH A del Portillo
Feb 21, 2002·Trends in Parasitology·Sanjai KumarStephen L Hoffman
Jun 14, 2001·International Journal for Parasitology·D L Doolan, S L Hoffman

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