Protection of the renal collecting system during radiofrequency ablation with antegrade cold dextrose infusion

Radiology
Sung Il HwangJae Young Byun

Abstract

To evaluate the feasibility and efficacy of antegrade renal cooling during radiofrequency (RF) ablation to protect the renal collecting system in pigs. With the approval of the institutional animal care and use committee, RF ablation was planned bilaterally after nephrostomy in 20 kidneys from 10 domestic pigs. A coaxial assembly consisting of a 7-F pigtail catheter and a 12-F arterial sheath was placed at the renal pelvis. Cooled 5% dextrose in water solution was perfused in only one of the kidneys in each pig. A 17-gauge internally cooled tip RF electrode with a 3-cm tip was placed near the renal pelvis with ultrasonographic guidance. On postprocedural days 1 and 7, computed tomography (CT) was performed to evaluate the RF ablation effect, the presence of a fluid collection, and the leakage of contrast material. Ex vivo retrograde pyelography was performed to assess the integrity of the urinary tract after kidney harvest. Histologic findings related to the urothelial damage were scored semiquantitatively. The mean maximal diameter of the RF ablation area measured at CT and in specimens was not significantly different between cooled and noncooled kidneys. A fluid collection around the RF ablation area was seen in eight of the ...Continue Reading

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Citations

Oct 5, 2011·Abdominal Imaging·Jason D IannuccilliWilliam W Mayo-Smith
May 28, 2014·International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group·Hui GuoJian Li
Jul 28, 2013·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·Dong Hyun YooSeung Hyup Kim
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Jun 20, 2020·International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group·Giovanni MauriFranco Orsi
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Jul 1, 2021·Investigative and Clinical Urology·Byung Kwan ParkYi Wang
Aug 28, 2021·Korean Journal of Radiology : Official Journal of the Korean Radiological Society·Byung Kwan ParkYi Wang

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