PMID: 16613276Apr 15, 2006Paper

Protective effects of puerarin against myocardial injury in patients with hypertension during perioperational period

Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine
Xian-Ping WuWeicai Chen

Abstract

To investigate the protective effects of puerarin against myocardial injury in patients with hypertension during perioperational period. Thirty-four patients with hypertension underwent general anesthesia were randomly divided into the control group and the puerarin group, 500mg puerarin was given to the puerarin group 1hr before anesthesia induction by venoclysis and to the control group, normal saline was given instead. The concentration of serum cardiac troponin I (cTnI) and isoenzyme of creatine kinase containing M and B subunits (CK-MB) were measured before anesthesia induction and 2 hrs after operation respectively. The serum concentration of cTnI and CK-MB were insignificantly different in the two groups before induction, the two indexes increased in different degrees (P <0.01) 2 hrs after operation in both groups, but the increments in the puerarin group were significantly lower than those in the control group (P< 0.01). Stress of operation and anesthesia could induce myocardial injury in patients with hypertension, which can be prevented by puerarin medicated during perioperational period.

Related Concepts

Related Feeds

Cardiomyopathy

Cardiomyopathy is a disease of the heart muscle, that can lead to muscular or electrical dysfunction of the heart. It is often an irreversible disease that is associated with a poor prognosis. There are different causes and classifications of cardiomyopathies. Here are the latest discoveries pertaining to this disease.

Related Papers

Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine
Ya-li WangPing Jiang
Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine
Le-Hong JinYu Zeng
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
Fu-Wen WangYan-Ying Xie
Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials
Hai-ying ZhangXian-fang Zhang
Nan fang yi ke da xue xue bao = Journal of Southern Medical University
Shu-qin Cui
© 2022 Meta ULC. All rights reserved