Protective efficacy of Psidium cattleianum and Myracrodruon urundeuva aqueous extracts against caries development in rats

Pharmaceutical Biology
Taís Elisabete Crivelaro de MenezesE Gaetti-Jardim

Abstract

This study evaluated the influence of Psidium cattleianum Sabine (Myrtaceae) and Myracrodruon urundeuva Allemão (Anacardiaceae) aqueous extracts on S. mutans counts and dental enamel micro-hardness of rats submitted to a cariogenic challenge. Sixty Wistar rats were distributed in three groups and received water (control) or aqueous extracts of Psidium cattleianum or Myracrodruon urundeuva as hydration solution. Initially the animals had their sublingual and submandibular salivary glands surgically removed and the parotid ducts ligated. Then the rats were inoculated with 10(6) CFU of Streptococcus mutans ATCC 35668 and were fed with a cariogenic diet. To detect and quantify the presence of S. mutans, oral biofilms were sampled and microbial DNA was extracted and submitted to amplification by means of real-time PCR (Polymerase Chain Reaction). After seven weeks the animals were sacrificed and enamel demineralization was analyzed by cross-sectional micro-hardness. Both extracts produced a significant reduction on S. mutans counts and decreased the enamel demineralization. It can be concluded that the extracts tested had a significant effect on S. mutans in oral biofilm of the rats, decreasing S. mutans accumulation and enamel demi...Continue Reading

References

Nov 1, 1973·Archives of Oral Biology·O G GoldJ Van Houte
Nov 1, 1995·Antimicrobial Agents and Chemotherapy·J M Hamilton-Miller
Oct 9, 1999·Clinical Microbiology Reviews·M M Cowan
Jan 5, 2000·Journal of Ethnopharmacology·P JaiarjO Ruangsomboon
Aug 1, 2000·The Journal of the American Dental Association·J D Featherstone
Jan 1, 1988·Journal of Dental Research·W H BowenD A Young
May 3, 2003·Phytomedicine : International Journal of Phytotherapy and Phytopharmacology·G S B VianaF J A Matos
May 25, 2004·European Journal of Oral Sciences·Michiyo MatsumotoTakashi Ooshima
Aug 25, 2004·Journal of Ethnopharmacology·S S HebbarG R Hegde
Sep 24, 2004·Journal of Medicinal Food·Farid A Badria, Omar A Zidan
Nov 2, 2004·Biological & Pharmaceutical Bulletin·Denise Pimenta da Silva LeitãoAugusto César Cropanese Spadaro
Mar 7, 2006·Community Dentistry and Oral Epidemiology·Gisela Ladda Tayanin, Douglas Bratthall
Aug 8, 2006·Archives of Oral Biology·Fabíola Galbiatti de CarvalhoDenise Madalena Palomari Spolidorio
Sep 14, 2006·Revista Panamericana De Salud Pública = Pan American Journal of Public Health·Paulo Capel NarvaiJosé Leopoldo F Antunes

❮ Previous
Next ❯

Citations

Aug 24, 2017·BMC Complementary and Alternative Medicine·Ítalo Diego Rebouças de AraújoVânia Sousa Andrade
Apr 8, 2021·Phytotherapy Research : PTR·Betina M BeltrameAmélia T Henriques

❮ Previous
Next ❯

Related Concepts

Related Feeds

Biofilm & Infectious Disease

Biofilm formation is a key virulence factor for a wide range of microorganisms that cause chronic infections.Here is the latest research on biofilm and infectious diseases.