Protective potentials of a potentized homeopathic drug, Lycopodium-30, in ameliorating azo dye induced hepatocarcinogenesis in mice

Molecular and Cellular Biochemistry
Surajit PathakAnisur Rahman Khuda-Bukhsh

Abstract

The protective potentials of a potentized homeopathic drug, Lycopodium-30, prepared from extract of spores of a plant, Lyocopodium clavatum (Fam: Lycopodiaceae) and used as a remedy for various liver ailments, have been tested in mice chronically fed p-dimethyl amino azo benzene (p-DAB) - an initiator, and phenobarbital (PB) - a promoter of hepatic cancer, by using some cytogenetic endpoints like chromosome aberrations (CA), micronuclei (MN), mitotic index (MI) and sperm head abnormality (SHA), and toxicity biomarkers like acid and alkaline phosphatases (AcP and AlkP, respectively), alanine and aspartate amino transferases (ALT and AST, respectively) and lipid peroxidation (LPO) and reduced glutathione (GSH) activities. The effects of chronic treatment of the carcinogens were assessed at different intervals of fixation, namely, at day 7, 15, 30, 60, 90 and day 120, and compared with that of mice fed conjointly with the carcinogens and the homeopathic remedy. Both the assay systems indicated considerable protective potentials of the homeopathic remedy against p-DAB induced hepatocarcinogenesis in mice.

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Citations

Aug 28, 2007·Journal of Veterinary Medicine. A, Physiology, Pathology, Clinical Medicine·P BanerjeeA R Khuda-Bukhsh
Jun 13, 2019·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Richard L JayarajFakhreya Yousuf Jalal
May 13, 2020·Journal of Basic and Clinical Physiology and Pharmacology·Antara BanerjeeSusmita Roy
Nov 15, 2006·Integrative Cancer Therapies·Rajesh L ThangapazhamWayne B Jonas
Aug 3, 2010·Homeopathy : the Journal of the Faculty of Homeopathy·Antara BanerjeeAnisur Rahman Khuda-Bukhsh
Jun 29, 2007·Forschende Komplementärmedizin = Research in Complementary Medicine·Surajit PathakAnisur Rahman Khuda-Bukhsh
Jan 13, 2015·Homeopathy : the Journal of the Faculty of Homeopathy·Gustavo Henrique da SilvaMatheus Arnosti Landi
Dec 1, 2009·Homeopathy : the Journal of the Faculty of Homeopathy·Anisur Rahman Khuda-Bukhsh
Feb 5, 2010·Homeopathy : the Journal of the Faculty of Homeopathy·Leoni Villano Bonamin, Peter Christian Endler
Apr 23, 2014·Global Advances in Health and Medicine : Improving Healthcare Outcomes Worldwide·Iris R BellJohn Ives
Aug 1, 2008·Expert Opinion on Drug Discovery·Anisur Rahman Khuda-Bukhsh, Surajit Pathak
Dec 20, 2014·Evidence-based Complementary and Alternative Medicine : ECAM·Ilaria MarottiGiovanni Dinelli
Jul 21, 2009·Evidence-based Complementary and Alternative Medicine : ECAM·Anisur Rahman Khuda-BukhshPhilippe Belon
Jun 15, 2011·Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine·Anisur Rahman Khuda-BukhshNaoual Boujedaini
Nov 15, 2006·Integrative Cancer Therapies·Anisur R Khuda-Bukhsh
Dec 22, 2020·Homeopathy : the Journal of the Faculty of Homeopathy·Andreza Pereira Dos SantosLeoni Villano Bonamin
Aug 27, 2013·Journal of Acupuncture and Meridian Studies·Asmita SamadderAnisur Rahman Khuda-Bukhsh
Aug 18, 2012·Journal of Acupuncture and Meridian Studies·Nandini Bhattacharjee, Anisur Rahman Khuda-Bukhsh
Apr 4, 2021·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Aleksandra DymekTomasz Mroczek
Dec 27, 2006·Experimental and Molecular Pathology·Surajit Pathak, Anisur Rahman Khuda-Bukhsh
Jan 25, 2008·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·S J BiswasA R Khuda-Bukhsh
Oct 9, 2009·Ecotoxicology and Environmental Safety·Abhishek MukherjeeAnisur R Khuda-Bukhsh

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